Core Facilities | CHOP Research Institute

Core Facilities

The Aquatic Zebrafish Core provides services using the small vertebrate zebrafish as a model for human disease and to study gene function.

The Biorepository Resource Center assists investigators, divisions, and centers in the collection, tracking, storage, processing, and distribution of biobanked specimens across CHOP Research Institute.

If you need to ensure your study includes valid, statistically sound data and results, then the Biostatistics and Data Management Core (BDMC) at Children’s Hospital is here to help!

Established in 2006, the CAG Biorepository is one of the world’s largest and most diverse pediatric biobanks, hosting more than 600,000 biological samples that have been genotyped or sequenced in CAG’s CLIA and CAP-accredited high-throughput centers. This core offers DNA and RNA extraction services.

Established in 2006, the CAG Genotyping Laboratory is fully equipped with state-of-art technology and experienced staff members. Our lab is integrated with our Biorepository and Bioinformatics group, keeping all stages of collaborators’ studies connected.

The CAG Sequencing Laboratory is fully equipped with state-of-art technology and expert staff members. Intergrated sequencing operations with our Biorepository and Bioinformatics teams to keep all stages of a collaborator’s studies connected. The lab also offers cutting-edge technologies in genomics.

Looking for help with sequencing and analytics to advance your project? The CHOP Microbiome Center is the sequencing and analytical resource of the PennCHOP Microbiome Program, providing end-to-end solutions for microbiome research.

The CHOP-Penn Proteomics Core provides a variety of protein and proteomics services for investigators at Children’s Hospital of Philadelphia, University of Pennsylvania, and outside institutions.

The Raymond G. Perelman Center for Cellular and Molecular Therapeutics has established state-of-the-art Current Good Manufacturing Practices (cGMP) clinical vector manufacturing suites for adeno-associated virus (AAV) and lentiviral (LV) vectors.

The Comparative Medicine Services Core partners with and guides investigators through the process of translating their wet bench research into clinical care to improve the lives of patients and families.

Advance the quality and scope of your research with easy access to state-of-the-art flow cytometers and professional services at the Flow Cytometry Core Laboratory.

The High Throughput Sequencing Core provides access to next-generation sequencing on Illumina® platforms. The staff provides consultation on experimental design, library preparation, and sequencing parameters for a broad range of projects. We are here to listen and create solutions.

The Human Pluripotent Stem Cell Core provides services for the development of novel, human cell-based experimental models for elucidating the pathophysiology of genetic disorders.

The Large Animal Imaging Facility Core provides infrastructure to support translational research activities that bring diagnostic and therapeutic drugs and interventions, investigational new drugs, and investigational device exemption from bench to bedside in an efficient and cost-effective manner.

If you’re in need of advanced state-of-the-art pathology services to propel your research, you’ll want to meet with our experts at the Pathology Core Laboratory.

The Qualitative Research Core supports qualitative and mixed-method research. We assist researchers with defining research questions, conceptualizing sampling strategies, selecting and designing appropriate data collection methods, and executing qualitative work.

The Research Staffing Core provides clinical research personnel to support all types of clinical research studies and excels at matching top quality clinical research staff with clinical investigators and teams.

The Research Vector Core provides state-of-the-art technology support for investigators requiring viral-based vectors for gene transfer in basic research and pre-clinical studies.

The Single Cell Technology Core specializes in state-of-the-art single cell technologies and the analysis of complex data sets. We facilitate transcriptomic, epigenomic, and spatial-omic experiments.

When you’re in need of radiological imaging for your research, look no further than the Small Animal Imaging Facility at Children’s Hospital.

The Small Molecule and Metabolite Core is focused on assay development, validation, and sample analysis utilizing the latest mass spectrometry techniques.

The Transgenic Core at Children’s Hospital Research Institute can build you complex mouse or rat models, genetically manipulating the mouse or rat genome to meet your specific research needs.

The Translational Core Laboratory (TCL) provides laboratory testing and specimen processing services to support clinical research and animal studies.

Core Facilities Administration