Children’s Hospital of Philadelphia is a leading site in the U.S. for world-changing pediatric clinical studies. We have a robust portfolio of active clinical research working with diverse patient populations across a variety of study types and fields. Comprehensive administrative research support ensures researchers at all levels perform highly productive, cost-effective studies that prioritize the patient-family experience. With the help of patients and healthy control participants, we’re finding answers to common, complex conditions and the rarest pediatric diseases. Check out our Research Discovery Finder for more information.
- CHOP Research Institute is one of the nation’s largest recipients of National Institutes of Health funding made available to pediatric hospitals.
- Annually, CHOP Research Institute has between 2,500 and 2,600 investigator-initiated, industry- and federally-sponsored, and foundation-supported IRB active protocols.
- CHOP developed the first two FDA-approved gene therapies. Currently, more than two dozen cell and gene therapy trials are enrolling patients at CHOP.
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Our team is working on a study to better understand neurological problems, including seizures and developmental delays, that occur in children with hyperinsulinism, including HI/HA syndrome, and type 1 diabetes mellitus.
The goal of this research study is to compare sex and gender development differences between children ages 4-8 years who are on the autism spectrum with children who are not on the autism spectrum.
The purpose of this research study is to learn more about the safety and effects of CTX001 (the “Study Product”) in patients ages 12 to 35 years who have been diagnosed with severe sickle cell disease.
Study focusing on non-invasive MRI procedures to measure biological activity within leg muscles of individuals, including both healthy volunteers and those with mitochondrial disease.
The purpose of this research study is to figure out if a new smartphone app impacts distracted driving, and to learn parent and teen perspectives on the app.
This study aims to support families with buying, cooking, and eating fresh fruits and vegetables at home! The goal of this study is to learn how fruit and vegetable vouchers and virtual cooking classes and resources affect families' experiences with home cooking and food shopping, as well as caregiver mental health.