Comparative Medicine Services Core

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The mission of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics Comparative Medicine Services Core is to partner with and guide Children’s Hospital of Philadelphia-based and external investigators through the process of translating their wet bench research to clinical care.

Since its inception, CHOP Research Institute has held a bench-to-bedside philosophy that emphasizes bringing basic research ideas to the clinic so they may improve the lives of our patients and their families. Completing preclinical investigations and submitting Investigational New Drug and Premarket Approval Applications to the U.S. Food and Drug Administration to initiate first-in-human trials are essential steps toward enacting this philosophy.

The Comparative Medicine Services Core is currently developing the capacity for Good Laboratory Practice (GLP) compliance. Fully GLP-compliant services will begin in the second quarter of 2022; however, all preclinical programs require in-depth planning and discussion. Therefore, we encourage you to contact us as soon as you believe you have a drug or device that will eventually require human clinical trials prior to use in patients. The Comparative Medicine Services Core comprises highly trained veterinary, regulatory, and quality assurance professionals capable of completing and overseeing a variety of studies working with animal models. We adhere to the highest standards of animal welfare, procedure reproducibility and validation, and customer service.