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Division of Rheumatology Research Studies
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Abatacept Registry
The purpose of this registry is to study the long-term effects and safety of Abatacept(Orencia) as used for the treatment of Juvenile Idiopathic Arthritis(JIA). JIA patients that are currently taking Abatacept may be eligible to participate in this study.
Defining Clinically Meaningful Outcome Measures For Children With Axial Juvenile Spondyloarthritis
The purpose of this study is to find out how well surveys can measure disease activity in kids with lower back arthritis. The study will last for either 3 or 6 months and take 2 or 3 visits.
Healthy Controls EndoPAT
The purpose of this research study is to learn more about the normal function of blood vessels in healthy children and adolescents.
ILAR Reclassification Study
This study hopes to revise the currently used criteria for diagnoses of Juvenile Idiopathic Arthritis (JIA).
Longitudinal ABP And Atherosclerosis In PSLE
The purpose of this study is to learn how to monitor heart health in children and teens with lupus.
MAS825 Trial for NLRC4-GOF
The purpose of this study is to find out if the study drug, MAS825, is effective in preventing flares and safe for children with NLRC4-Gain of Function (GOF).
Pediatric Normative Data for the Complete Minnesota Dexterity Test
The Division of Rheumatology at CHOP is looking to engage healthy participants for several research studies with the goal of learning more about ways to improve the health and well-being of children and young adults.
Therapeutic use of Tadekinig alfa in NLRC4 mutation and XIAP deficiency
This is a clinical trial to study the use of Tadekinig alfa or placebo (medication) in the treatment of NLRC4 MAS mutation or XIAP deficiency.
Upadacitinib Trial for Polyarticular JIA
The purpose of this study is to see if a new investigational drug (Upadacitinib) is safe and well tolerated and also to determine the appropriate dose for subjects with polyarticular course juvenile arthritis (pcJIA).
VOCAL Trial
This is a study to measure the effectiveness of the medication voclosporin compared to placebo in adolescent patients with active lupus nephritis.