Chromatin | CHOP Research Institute
 

Chromatin

Weitzman Laboratory

Weitzman Lab

Research in the Weitzman Lab aims to understand host responses to virus infection, and the cellular environment encountered and manipulated by viruses. The lab studies multiple viruses in an integrated experimental approach that combines biochemistry, molecular biology, genetics, and cell biology.

Blobel Laboratory

Blobel Laboratory

The Blobel Lab investigates the fundamental mechanisms involving transcription factors, chromatin regulators, and higher order chromatin, gearing its basic science discoveries toward genetic and epigenetic treatment modalities.

Scientists Reveal New Mechanism Adenovirus Uses to Sabotage Immune System

Published on
Jun 30, 2016
in Cornerstone Blog
Adenovirus, a common human virus that usually affects the lungs and causes respiratory tract infections, is an old friend to virologists. They have long studied how this virus interacts with host cells to understand cellular processes and reveal key regulators of cellular functions.

Forced Looping Viable Strategy to Reverse Globin Switch

Published on
Aug 15, 2014
in Cornerstone Blog
Investigators at The Children’s Hospital of Philadelphia are exploring a new gene therapy approach that aims to reactivate the production of fetal hemoglobin as a potential intervention for patients with sickle cell disease.