Stem Cells | CHOP Research Institute

Stem Cells

Published on
Jan 12, 2024
The Cell and Gene Therapy Lab at CHOP has been approved for a phased expansion project that will allow them to keep up with the pace of discovery in a rapidly changing field.
Published on
Oct 20, 2023
Researchers found exposing cells to a small molecule drug improves cell fitness during hematopoietic stem cell transplants, which could improve ex vivo gene therapy.

The Thom Lab, an integrated genomics and cell biology lab, aims to define novel factors that regulate blood cell development and function in order to augment in vitro blood cell production.

The purpose of this research study is to find out if stem cells from umbilical cord blood can strengthen the muscle of the right side of the heart for patients diagnosed with Hypolplastic Left Heart Syndrome who are scheduled to undergo the Stage II Glenn surgical procedure.

The Gadue Lab studies human pancreatic and hematopoietic development and associated diseases using human pluripotent stem cells. The lab’s research efforts are devoted to directed differentiation and CRISPR-based genome engineering of stem cells to use in the study and development of treatments for diabetes and blood disorders.

Exploring the possibilities for treating disorders during fetal development.

Investigating limbic circuitry, mental function, and new neurons of the postnatal brain (Lab LMNoP).

Research in the Akizu Lab uses cutting-edge technologies to uncover genetic and epigenetic mechanisms of developmental brain disorders and advance diagnostic and treatment strategies.

Published on
Mar 12, 2021
Our March featured faculty member, Kathryn Hamilton, PhD, studies gastrointestinal epithelial stem cells.
Published on
Oct 15, 2020
Peter Kurre, MD, seeks to determine to what extent defects in fetal blood forming cells accelerate the loss of bone marrow function in young patients.