About Penn-CHOP Kidney Innovation Center



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The prevalence of kidney disease has continued to rise steadily, and the lack of critical new discoveries has hindered the delivery of optimal medical care and treatments to affected individuals. Children's Hospital of Philadelphia and the University of Pennsylvania have a long-standing commitment to conduct research that improves the lives of children and adults with kidney disease.


The Penn-CHOP Kidney Innovation Center's mission is to conduct research that will improve the lives of children and adults with kidney disease.


The Center’s collaboration between Penn and CHOP is focused on ultimately transforming patient care by early detection, prevention and treatment of kidney disease and its complications across the life course.

CHOP's Division of Nephrology has a special interest in children with cystic kidney diseases, nephrotic syndrome, lupus nephritis and other vasculitides, genetic renal disorders, renal tubulopathies, hypertension, acute kidney injury, and chronic kidney disease. Since 2017, CHOP is home to an NIDDK-funded Pediatric Center of Excellence in Nephrology that supports research aimed at breaking down barriers to clinical trials in children with kidney disease.

The University of Pennsylvania has long been a place for world class kidney research. Alfred Newton Richards was credited with the method of renal micropuncture to study the functioning of kidneys. He served as chairman of the department of pharmacology from 1910 to 1946 and was the university's vice-president of medical affairs from 1939 to 1948. Later an O'Brien Kidney Center was established under the leadership of Eric Nelson and was continued by Lawrence Turka. Penn Nephrology is viewed as a critical scientific leader in nephrology.