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Additional Ventures Single Ventricle Research Fund Program

Published on August 31, 2020 in Announcements · Last updated 4 months 2 weeks ago


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Additional Ventures is accepting Letters Of Intent (LOI) for its inaugural Single Ventricle Research Fund (SVRF) program. The SVRF program is solely focused on accelerating and improving care for those with single ventricle heart defects. The multi-year (up to three-year), high-impact grants are intended to identify biomarkers and/or functional tools to map end-organ function in single ventricle patients, and to assess non-invasive interventional strategies to treat or prevent clinical sequelae in these patients.


Eligible individuals must hold a doctoral degree (PhD, MD, PsyD, or equivalent doctorate) and can be independent investigators, research postdoctoral, or medical fellows.


Applications should focus on studies that achieve one or more of the following goals:

  • Identification of biomarkers and development of predictive tools and/or functional diagnostics to understand, track, and optimize end-organ function to further precision medicine in single ventricle patients.
  • Identification and validation of non-invasive interventions (e.g., diet, exercise, neurocognitive approaches, and lifestyle factors) to address and/or prevent clinical sequelae observed in single ventricle patients.

LOIs must be submitted through the Additional Ventures online portal. There is a submission template within the portal and the LOI itself is limited to one page, submitted in PDF format, and should outline the applicant's interest in submitting a full-length proposal. It should include a brief description of the project, including the primary hypothesis and goals of the proposed research.

To Apply

The deadline for the LOI is 5:00 p.m. EST, September 18, 2020.

Successful LOI applicants will be invited by 5:00 p.m. September 22, 2020 to submit a full proposal by 5:00 p.m. October 22, 2020.

The award provides up to $200,000 direct costs per year for three years. An additional 10 percent will be awarded for institutional indirect costs.

See the attached RFA and for more information about this opportunity.