Moving Bold Ideas Forward
Since 1922, the Research Institute has pursued excellence in scientific discovery and medical innovation to create solutions for the most challenging problems in children’s health. We’ve come a long way since then, and in 2022, we celebrated progress in cell and gene therapy, introduced interventions for rare diseases, and launched new collaborations and partnerships that are driving breakthroughs to transform children’s healthcare for many years to come.
Brenda Banwell, MD, chief of the Division of Neurology and co-director of the new Neuroscience Center, describes the unparalleled breadth and depth of experience at Children’s Hospital of Philadelphia Research Institute, where our investment in excellence powers new discoveries, new diagnoses, and new therapies for families all over the world.
In 2022, CHOP’s focus on rare and complex diseases led to the Canadian approval of a new drug to treat the ultra-rare bone disorder FOP and an experimental prodrug to treat high-risk neuroblastoma.
Two new Frontier Programs launched in 2022 to study treatments for heart failure and hemophilia, and the FDA granted Fast Track Designation to a new treatment for Friedreich’s Ataxia.
Highlights of the year include the development of a tool called BrainChart that uses magnetic resonance imaging data to provide benchmarks of brain development over the human lifespan.
From The Susan S. and Stephen P. Kelly Center for Cancer Immunotherapy to the Philadelphia Regional Center for Children’s Environmental Health, new initiatives are setting the pace of discovery.
Join us in turning back the clock 100 years as we tell the storied history of CHOP Research Institute. One thing hasn’t changed: our reputation as pioneers in children’s health.
In 2022, we marked a major milestone for Children’s Hospital of Philadelphia Research Institute: 100 years of research! In a special section of the Annual Report, discover our proud history of groundbreaking research advancements and the people behind them whose collective goal — then and now — is to give every child the best opportunity for a bright future.