Structural Biology | CHOP Research Institute
 

Structural Biology

Published on
Jan 20, 2025
CHOP researchers are the first to capture a structural snapshot of an MHC-I molecule as it screened for peptides, a critical immune system process.

Revealing new mechanistic insights into the multiple facets of why factor VIII inhibitors form as an immune response to protein replacement therapy to treat hemophilia A.

The Mechanistic Molecular Immunology Lab integrates cutting-edge structural biology and biochemistry tools with functional immunoassays to understand the molecular basis of immune responses to viral infections and tumors, with an emphasis on the development of novel protein-based therapeutics.

Published on
Aug 8, 2018
New FVIII Center has four projects under way from diverse perspectives to find novel approaches for therapeutic intervention in hemophilia A.