Macrophages

The Rivella Laboratory uses lentiviral vectors for modulation of gene expression and gene transfer for the cure of hemoglobinopathies.

Scientists in the Hill Lab seek to understand how the immune system contributes to the two most common chronic diseases of childhood: allergy and obesity. The lab uses clinical and epidemiological information to guide basic and translational research aimed at understanding the genetic, epigenetic, and immunologic basis of these diseases.

Steven D. Douglas, MD, and his laboratory team investigate the immunopathogenesis of HIV/AIDS in relation to monocytes/macrophages, immune activation, immune suppression, and inflammation. The laboratory also has projects which examine the role of the neurokinin-1 receptor in inflammation and depression.

All biological processes operate under biochemical constraints. The Bailis Lab aims to understand how metabolism controls the development and functional differentiation of the hematopoietic system by setting the biochemical potential of cells and tissues, using in vitro and in vivo CRISPR screening in primary immune cells.