In This Section

thomc [at]
Location - People View
10th Floor, Room 10-052

3615 Civic Center Blvd
Philadelphia, PA 19104
United States

Research Topics
Christopher S. Thom, MD, PhD
Christopher S. Thom
Principal Investigator

Dr. Thom uses computational and cellular approaches to understand genetic determinants of hematopoiesis. Dr. Thom aims to harness related insights to improve in vitro blood cell production from induced pluripotent stem cells.



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Education and Training

BA, Williams College (Chemistry), 2006

PhD, University Of Pennsylvania (Cell And Molecular Biology), 2015

MD, University Of Pennsylvania, 2015

Residency, Children’s Hospital of Philadelphia (Pediatrics)

Fellowship, Children’s Hospital of Philadelphia (Neonatology)

Titles and Academic Titles

Principal Investigator

Attending Physician

Assistant Professor of Pediatrics

Professional Memberships

American Academy of Pediatrics, 2015-

Society for Pediatric Research, 2017-

Trainees and Early Career Neonatologists, 2019-

American Society of Hematology, 2019-

Professional Awards

Hartwell Individual Biomedical Research Award, Hartwell Foundation, 2022

American Academy of Pediatrics Section on Neonatal and Perinatal Medicine Young Investigator Award, 2021

62nd American Society of Hematology Conference Abstract Achievement Award, 2020

Society for Pediatric Research Fellows’ Basic Research Award, 2020

Eastern Society of Pediatric Research Trainee Young Investigator Award, 2020

Children’s Hospital of Philadelphia Distinguished Research Trainee Award, 2020

61st American Society of Hematology Conference Abstract Achievement Award, 2019

American Academy of Pediatrics Trainees and Early Career Neonatologists Travel Award, 2019

Philadelphia Perinatal Society Thomas R Boggs Award for Neonatal-Perinatal Research, 2019

American Academy of Pediatrics Marshall Klaus Perinatal Research Award, 2019

Publication Highlights

Gu H, Devine M, Hedrick HL, Rintoul NE, Thom CS. High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients. Platelets. 2022 Jul; 33(5): 787-789. PubMed PMID: 34697983
Lorenz K, Thom CS, Adurty S, Voight BF. TSABL: Trait Specific Annotation Based Locus predictor. BMC Genomics. 2022 Jun; 23(1): 444. PubMed PMID: 35705896
Thom CS, Wilken MB, Chou ST, Voight BF. Body mass index and adipose distribution have opposing genetic impacts on human blood traits. Elife. 2022 Feb; 11: e75317. PubMed PMID: 35166671
Thom CS, Brandsma E, Lambert MP. Thrombocytosis in an infant with a TRPV4 mutation: a case report. Platelets. 2021 Apr; 32(3): 429-431. PMID: 32319342
Thom CS, Echevarria E, Osborne AD, Carr L, Rubey K, Salazar E, Callaway D, Pawlowski T, Devine M, Kleinman S, Flibotte J, Lambert MP. Extreme thrombocytosis is associated with critical illness and young age, but not increased thrombotic risk, in hospitalized pediatric patients. J Thromb Haemost. 2020 Dec; 18(12): 3352-3358. PMID: 32979018