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In This Section
Christopher S. Thom, MD, PhD
Principal Investigator
Dr. Thom uses computational and cellular approaches to understand genetic determinants of hematopoiesis. Dr. Thom aims to harness related insights to improve in vitro blood cell production from induced pluripotent stem cells.
Education and Training
BA, Williams College (Chemistry), 2006
PhD, University Of Pennsylvania (Cell And Molecular Biology), 2015
MD, University Of Pennsylvania, 2015
Residency, Children’s Hospital of Philadelphia (Pediatrics)
Fellowship, Children’s Hospital of Philadelphia (Neonatology)
Titles and Academic Titles
Principal Investigator
Attending Physician
Assistant Professor of Pediatrics
Professional Memberships
American Academy of Pediatrics, 2015-
Society for Pediatric Research, 2017-
Trainees and Early Career Neonatologists, 2019-
American Society of Hematology, 2019-
Professional Awards
Hartwell Individual Biomedical Research Award, Hartwell Foundation, 2022
American Academy of Pediatrics Section on Neonatal and Perinatal Medicine Young Investigator Award, 2021
62nd American Society of Hematology Conference Abstract Achievement Award, 2020
Society for Pediatric Research Fellows’ Basic Research Award, 2020
Eastern Society of Pediatric Research Trainee Young Investigator Award, 2020
Children’s Hospital of Philadelphia Distinguished Research Trainee Award, 2020
61st American Society of Hematology Conference Abstract Achievement Award, 2019
American Academy of Pediatrics Trainees and Early Career Neonatologists Travel Award, 2019
Philadelphia Perinatal Society Thomas R Boggs Award for Neonatal-Perinatal Research, 2019
American Academy of Pediatrics Marshall Klaus Perinatal Research Award, 2019
Publication Highlights
Gu H, Devine M, Hedrick HL, Rintoul NE, Thom CS. High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients. Platelets. 2022 Jul; 33(5): 787-789. PubMed PMID: 34697983
Lorenz K, Thom CS, Adurty S, Voight BF. TSABL: Trait Specific Annotation Based Locus predictor. BMC Genomics. 2022 Jun; 23(1): 444. PubMed PMID: 35705896
Thom CS, Wilken MB, Chou ST, Voight BF. Body mass index and adipose distribution have opposing genetic impacts on human blood traits. Elife. 2022 Feb; 11: e75317. PubMed PMID: 35166671
Thom CS, Brandsma E, Lambert MP. Thrombocytosis in an infant with a TRPV4 mutation: a case report. Platelets. 2021 Apr; 32(3): 429-431. PMID: 32319342
Thom CS, Echevarria E, Osborne AD, Carr L, Rubey K, Salazar E, Callaway D, Pawlowski T, Devine M, Kleinman S, Flibotte J, Lambert MP. Extreme thrombocytosis is associated with critical illness and young age, but not increased thrombotic risk, in hospitalized pediatric patients. J Thromb Haemost. 2020 Dec; 18(12): 3352-3358. PMID: 32979018