HRpQCT in Childhood Osteoporosis



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Are you interested in participating in a research study about bone health in children and adolescents at high risk of suffering a broken bone? Dr. Weber at CHOP is looking for people between 5-19 years old with a genetic or a long-term medical condition affecting bone strength to participate in this study. We are also recruiting children between 5-19 years old with no medical conditions as healthy participants in the study. Participation will require a single visit at The Children's Hospital of Philadelphia, which will include bone scans, a muscle strength evaluation by a physical therapist, blood and urine tests, and questionnaires. Eligible participants who complete the study will be compensated for their time. 

Who Do I Contact?

If you are interested in participating in the study or want to learn more please contact our study team at DavidWeberResearch [at] or 267-207-1666.

Eligibility & Criteria

IRB #:
Official Title:
Establishing the Relationship Between Muscle and Bone Outcomes in Children at High Risk of Skeletal Fragility
Study Phase:
Eligible Age Range:
5 - 19 Years

Visit Criteria

The study visit takes about 3 hours and will include: 

  • 3 bone scans (DXA scan, peripheral quantitative computed tomography of lower leg, high-resolution peripheral quantitative computed tomography of the lower leg) 
  • Physical therapy assessment of muscle strength 
  • Blood test
  • Urine test
  • Brief physical exam 
  • Questionnaires about health, medical history, diet, and activity