CrCEST MRI in Mitochondrial Disease



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The Mitochondrial Medicine Program at the Children's Hospital of Philadelphia is conducting a study focusing on non-invasive MRI procedures to measure biological activity within leg muscles of individuals, including both healthy volunteers and those with mitochondrial disease. This type of MRI is for research only, and it is not currently approved by the FDA. There is no direct benefit, but this research may contribute to future mitochondrial medicine. Your participation will last for approximately half a day during a visit at CHOP. We hope this research will contribute to the current knowledge of mitochondrial disease and improve diagnostic approaches. To learn more or inquire about this research study, please contact Sara Nguyen ([email protected])

Who Do I Contact?

If you are interested in participating in the study or want to learn more please contact our study team at nguyens2 [at] or 267-426-1986.

Eligibility & Criteria

IRB #:
Official Title:
Magnetic Resonance imaging (MRI) Muscle Phenotyping in Mitochondrial Disease
Study Phase:
Not Applicable
Eligible Age Range:
7 - 75 Years

Visit Criteria

A single visit will last approximately half a day at CHOP, and includes medical history review, MRI scan(s), and safety assessment.


Zarazuela Zolkipli-Cunningham