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Cornerstone Blog
What Is the Metabolic Mechanism of Brain Functional Development During Infancy?
Published on
Jan 29, 2025
This Snapshot Science reveals how cerebral blood flow maps indicate an emergence of physiological cortical hierarchy during infancy.
Cornerstone Blog
Can Gene Therapy Improve Long-term Cardiac Outcomes for Patients with Danon Disease?
Published on
Jan 27, 2025
Early Phase 1 trial results show potential for gene therapy to improve long-term cardiac outcomes.
Cornerstone Blog
What is the Role of MHC-I Proteins in Immune Surveillance?
Published on
Jan 20, 2025
CHOP researchers are the first to capture a structural snapshot of an MHC-I molecule as it screened for peptides, a critical immune system process.
Cornerstone Blog
CHOP Researchers Pioneer Gene Therapy to Treat XLSA in a Preclinical Model
Published on
Jan 14, 2025
In a preclinical model, the team reversed symptoms of X-linked sideroblastic anemia, a rare disorder.
Cornerstone Blog
Can Endothelial Cells Lining Veins In Lungs Help Repair Injured Blood Vessels?
Published on
Dec 16, 2024
Dr. David Frank and a team of researchers found that pulmonary venous endothelial cells contribute to the repair of blood vessels after lung injury.
Cornerstone Blog
Could Benefits Outweigh Risks of Vaccinating NICU Patients Against Rotavirus?
Published on
Dec 10, 2024
A Snapshot Science sums up how researchers explored rates of vaccine-strain rotavirus transmission in CHOP’s neonatal intensive care unit.
Cornerstone Blog
Could DLK1 Be an Immunotherapeutic Target to Treat Neuroblastoma?
Published on
Nov 6, 2024
Researchers identify cell surface protein DLK1 as a potential immunotherapeutic target for neuroblastoma.
Cornerstone Blog
What Are the Genomic Drivers of Childhood T-ALL?
Published on
Sep 30, 2024
CHOP researchers uncovered 15 subtypes of T-cell acute lymphoblastic leukemia, which will help to predict outcomes and guide treatment.
Cornerstone Blog
How Can We Improve Gene Therapy to Treat Hemophilia A?
Published on
Sep 19, 2024
CHOP researchers developed a factor VIII variant that led to safe and long-lasting therapeutic results in preclinical models.
Cornerstone Blog
Can High-Throughput Assays Help Classify Uncertain Variants?
Published on
Aug 15, 2024
In this Snapshot Science, researchers use high-throughput assays to characterize thousands of variants associated with Alagille syndrome.
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