Bioinformatics | CHOP Research Institute

Researchers Building Childhood Cancer Isoform Atlas to Find Immunotherapy Targets

Published on

Jan 29, 2024

Researchers Building Childhood Cancer Isoform Atlas

With funding from the National Cancer Institute’s Childhood Cancer Data Initiative, CHOP researchers are identifying new immunotherapy targets.

Mitochondria and Cancer Connections (MC²) Research Program

The Mitochondria and Cancer Connections (MC²) Research program leverages knowledge from existing centers to establish a novel, cutting-edge research initiative and enable the development of mechanistic understanding and novel therapeutic opportunities at the intersection of mitochondrial disease and pediatric cancer.

Tiffany Ko, PhD

Dr. Ko's research focus is the development of non-invasive diffuse optical tools to identify critical periods of neurological vulnerability and to facilitate individualized care pathways to mitigate subsequent neurological injury in critically-ill children.

E-mail:

kotiff [at] chop.edu

Featured Research Trainee: Allergy Bioinformatics With Megha Lal, PhD

Published on

Aug 3, 2023

in Cornerstone Blog

Our August Featured Research Trainee is Megha Lal, PhD, who investigates the mechanism of less common forms of food allergies such as eosinophilic esophagitis.

Wang Laboratory

Research in the Wang Laboratory focuses on the development of bioinformatics methods to improve the understanding of the genetic basis of human diseases, and the integration of electronic health records and genomic information to facilitate genomic medicine on scale.

Stephen R. Master, MD, PhD

Dr. Master works to understand the biochemical pathways related to inborn errors of metabolism, particularly as they relate to mitochondrial function. He also focuses on bioinformatics and machine learning solutions to problems in mass spectrometry and laboratory medicine.

E-mail:

masters [at] chop.edu

Department of Biomedical and Health Informatics

The Department of Biomedical and Health Informatics (DBHi) explores how data, technology, and knowledge converge to improve scientific research and patient care.

CHOP Microbiome Center

Looking for help with sequencing and analytics to advance your project? The CHOP Microbiome Center is the sequencing and analytical resource of the PennCHOP Microbiome Program, providing end-to-end solutions for microbiome research.

Yi Xing, PhD

Dr. Xing is the Executive Director of the Department of Biomedical and Health Informatics, the Francis West Lewis Chair and director of the Center for Computational and Genomic Medicine at CHOP, and professor of Pathology and Laboratory Medicine at the University of Pennsylvania. His research focuses on computational biology and genomics of RNA processing and regulation.

E-mail:

xingyi [at] chop.edu

Kai Wang, PhD

Dr. Wang's research focuses on the development of bioinformatics methods to improve the understanding of the genetic basis of human diseases, and the integration of electronic health records and genomic information to facilitate genomic medicine on scale.

E-mail:

wangk [at] chop.edu