Microbiome | CHOP Research Institute

CHOP Kidney Stone Center

The CHOP Kidney Stone Frontier Program integrates multidisciplinary clinical expertise in urology and nephrology with advanced multi-omics research to develop new diagnostic tests that will transform the management of children and adolescents with kidney stone disease.

Annavajhala Laboratory for Tracing Epidemics in Sewage

The Annavajhala Lab, also known as TRACES, is dedicated to understanding microbial dynamics in environmental systems. They use basic science and applied approaches in bioreactor models, hospital wastewater, and environmental sources to enable population-level pathogen surveillance.

Medini K. Annavajhala, PhD

Dr. Annavajhala is interested in the use of wastewater and environmental sampling to better understand pathogen-microbial community and pathogen-environment interactions. Her goal is to harness environmental surveillance to benefit population-level health.

E-mail:

annavajham [at] chop.edu

Cornerstone Blog

Center for Microbial Medicine Leverages ‘New Frontier’ for Pediatric Patients

Published on

Aug 28, 2024

The Center for Microbial Medicine will empower researchers to turn their discoveries in the microbiome space into therapeutic products for patients.

Center for Microbial Medicine

The Center for Microbial Medicine at Children’s Hospital of Philadelphia leverages the microbiome to improve the health of children and bring personalized microbiome-based medicine from bench to bedside to every child who receives care at CHOP.

Oral Desensitization

The purpose of this research study is to understand what happens to the immune systems and gut microbiomes (gut bacteria) of people who have a food allergy while they undergo an oral desensitization protocol.

Cornerstone Blog

Do Microbiota and T Cells Influence Epigenetic Inheritance of Phenotypes?

Published on

Apr 23, 2024

Microbiota, T Cells Influence Epigenetic Inheritance of Phenotypes

Researchers from CHOP and Penn reveal that the microbiome and immune system play a key role in the non-genetic transfer of phenotypes to offspring.

Zackular Laboratory

The Zackular Lab seeks to understand how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease.

Cornerstone Blog

NIH-funded Study Examines Interplay Between Immune Response and Antibiotic Dosage

Published on

Nov 20, 2023

Researchers Study Effects of Antibiotic Dosage on Immune Response

The NIH-funded study, PRESCRIBE, will help researchers understand how antibiotics affect organ function recovery and respiratory microbiota in children with sepsis.

Cornerstone Blog

Neonatal Pathogens and the Microbiome: Q&A With Diversity Fellow Haider Manzer, PhD

Published on

Nov 1, 2023

Q&A With Diversity Fellow Haider Manzer, PhD

We are highlighting Haider Manzer, PhD, one of four Diversity Fellows.