Stable Isotopes | CHOP Research Institute
 

Stable Isotopes

Published on
Apr 27, 2022
Dr. Nissim studies the relationship of the metabolome and the fluxome to the genome in normal and disease states.

Research in the Yudkoff Lab focuses on the use of stable isotopes to measure the rate of production of urea in humans who have a urea cycle defect or a congenital inability to detoxify ammonia into urea.

The Nissim Lab is led by a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and Nuclear Magnetic Resonance to study metabolome and fluxome and their coupling to genome in normal and disease states.

Dr. Nissim is a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and nuclear magnetic resonance to study metabolome and fluxome and their coupling to genome in normal and disease states. His long-standing interest focuses on understanding the cause, mechanisms, and outcome of metabolic disorders.

E-mail:
nissim [at] chop.edu