Epigenetics | CHOP Research Institute


The Center for Brain Research in Development, Genetics and Engineering (BRIDGE) applies innovative technology and advanced model systems to understand basic mechanisms of brain development and advance the implementation of novel therapeutics.

Published on
Jun 3, 2024
The CHOP-Penn Autism Research Symposium explored opportunities for breakthroughs in the understanding and treatment of autism spectrum disorder.
Published on
Apr 23, 2024
Researchers from CHOP and Penn reveal that the microbiome and immune system play a key role in the non-genetic transfer of phenotypes to offspring.

Dr. Wolpaw’s laboratory seeks to develop an understanding of how tumor heterogeneity and epigenetics impact inflammatory signaling and immunotherapy responses in pediatric solid tumors with a goal of developing more efficacious, less toxic therapies to treat these devastating diseases.

Published on
Jul 18, 2022
CHOP researchers develop tool that accelerates DNA methylation characterization.

The Center for Spatial and Functional Genomics is focused on uncovering the correct functional context of variants identified by genome-wide association studies in order to translate these discoveries into meaningful benefits for pediatric care.

Uncovering the correct functional context of genetic variants to translate genome-wide association studies into meaningful benefits for pediatric care.

Published on
Jan 13, 2022
Peter Choi, PhD, received the prestigious award for research into the hidden determinants of RNA splicing.
Published on
Dec 20, 2021
Dr. Carpenter’s research seeks to better understand how environmental factors affect the origins of disease via epigenetic modifications.
Published on
Aug 31, 2021
Our August Faculty Spotlight scientist, Naiara Akizu Lopez, PhD, studies the genetic and epigenetic mechanisms of neurologic disorders in children.