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Sivaramakrishnan Laboratory
We are hiring!
The Priya Sivaramakrishnan Lab opened on Jan. 1, 2024, at the Center for Computational and Genomic Medicine at CHOP and the Department of Pathology and Laboratory Medicine at Penn.
If you are interested in worm models and would like to work on any of our lab’s projects solving the mysteries of cell fate during development, email [email protected] to apply for a position
The Sivaramakrishnan Lab focuses on the primary step in gene expression, and transcription, and investigates mechanisms of transcriptional control that drive cell fate specification. All cells must integrate signals from the environment and make decisions on dealing with these external cues. The developing embryo allows us to explore how decision-making happens across multiple different cells simultaneously.
As a single-celled zygote divides and differentiates, we study which factors are necessary to ‘tell’ each cell whether they are destined to become muscle, skin, or the myriad of other cell types in the body. Gene expression programs are fundamental to these cell fate decisions.
