The goal of the study extension is to see whether the incretin hormone GIP increases insulin secretion in individuals with CF and normal glucose tolerance compared to individuals without CF and normal glucose tolerance.

The purpose of this research study is to collect different types of samples (such as stool, swabs, urine) to form a biorepository.

The purpose of the study is to evaluate blood sugar levels and beta-cell function in adolescents and adult with KATP hyperinsulinism whom did not undergo pancreatectomy.

To identify the underlying causes of bone marrow failure diseases for the purpose of developing and modifying treatment and diagnosis procedures.

This study will test whether supplemental oxygen therapy, a common post-discharge treatment for BPD, improves outcomes.

This study enrolls patients between 5 and 40 years of age with a diagnosis of Ewing sarcoma (including Ewing-like sarcoma) or osteosarcoma that has progressed on or relapsed after upfront initial therapy.

This two-phase study is being conducted to determine the reasons why some children with newly diagnosed Crohn's disease heal their bowel inflammation after one type of therapy and why others do not.

The goal of this study is to investigate the efficacy and safety of Canagliflozin (which is experimental) in children and adolescents ages 10 to 18 years old with Type 2 diabetes and poor control (i.e., an HbA1c of 6.5% to 10.5%).

This clinical trial is adding the study drug, Carfilzomib, to a standard relapse chemotherapy regimen.