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Humanized CART19 Phase 2 Trial
This purpose of this study is to determine the efficacy of humanized CD19 CAR T cells (huCART19) in pediatric and young adult patients with high-risk relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL).
Related PI: Shannon L. Maude, MD, PhD
Related Conditions: Relapsed Acute Lymphoblastic Leukemia, B Cells, Acute Lymphoblastic Leukemia, Gene Therapy
KTE-X19
This study will take the patients white blood cells - T cells - and change them to turn against the cancer.
Related PI: Stephan A. Grupp, MD, PhD
Related Conditions: Non-Hodgkins Lymphoma, B Cells, Oncology, Cancer, Adolescent and Young Adult Oncology Research, Gene Therapy
Phase 2 trial of CART19 for Orphan Indications Of Pediatric B Cell Acute Lymphoblastic Leukemia (B-ALL)
This is an open-label, four-cohort, phase 2 study to determine the efficacy of CART19.
Related PI: Amanda DiNofia, MD
Related Conditions: B Cells, Acute Lymphoblastic Leukemia, Oncology, CAR T Cell Therapy, Gene Therapy