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AAML1921; Bosutinib for Chronic Myeloid Leukemia
The overall goals of this study are to find the best dose of bosutinib that we can give safely, and to find out what effects, good and/or bad, bosutinib has on children and adolescents with Chronic Myeloid Leukemia (CML).
Related PI: Richard Aplenc, MD, PhD, MSCE
Related Conditions: Leukemia, Pediatric Leukemia, Oncology, Acute Myeloid Leukemia
CD33 CART AML

This phase 1/2 study will determine the safety, feasibility, and efficacy of CD33 CART cells following lymphodepleting chemotherapy in patients with acute myeloid leukemia (AML).
Related PI: Richard Aplenc, MD, PhD, MSCE
Related Conditions: Oncology, Acute Myeloid Leukemia , Leukemia, Gene Therapy