Research Discovery Finder

Children's Hospital of Philadelphia Research Institute is committed to improving the health and well-being of children in our community and across the world through advances in medicine and science. Your participation makes a difference in helping discover scientific breakthroughs and advancing care. Our research varies from innovative clinical trials to socio-behavioral research and studies you can complete from home. Check out some of our currently recruiting studies below or view past studies.

Did You Know?

Our scientists and staff aren’t the only ones who make breakthroughs happen. Many clinical trials would not succeed without patients, families, and individuals who volunteer to participate. See three little-known facts about participating in clinical research studies at Children’s Hospital of Philadelphia:

Most studies don’t involve drugs or devices. They include questionnaires, games, and learning about child development.
You don't have to travel to CHOP to participate in research. Some of our studies can be completed from home!
Knowledge gained through research helps improve the health and well-being of children in our community and around the world.

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AAML1921; Bosutinib for Chronic Myeloid Leukemia

The overall goals of this study are to find the best dose of bosutinib that we can give safely, and to find out what effects, good and/or bad, bosutinib has on children and adolescents with Chronic Myeloid Leukemia (CML).

Related PI: Richard Aplenc, MD, PhD, MSCE

Related Conditions: Leukemia, Pediatric Leukemia, Oncology, Acute Myeloid Leukemia

CD33 CART AML

This phase 1/2 study will determine the safety, feasibility, and efficacy of CD33 CART cells following lymphodepleting chemotherapy in patients with acute myeloid leukemia (AML).

Related PI: Richard Aplenc, MD, PhD, MSCE

Related Conditions: Oncology, Acute Myeloid Leukemia , Leukemia, Gene Therapy