Dr. Xing is the Francis West Lewis Chair and director of the Center for Computational and Genomic Medicine at CHOP, and professor of Pathology and Laboratory Medicine at the University of Pennsylvania. His research focuses on computational biology and genomics of RNA processing and regulation.
Dr. Pinney investigates the molecular mechanisms that link an adverse intrauterine milieu to the development of diabetes and obesity later in life. Specifically, she is researching how intrauterine growth restriction, gestational diabetes and in utero exposure to environmental toxicants contribute to the development of diabetes and obesity in offspring.
Dr. Wood's research focuses on improving health service delivery to reduce HIV and STI incidence in adolescents and young adults. Her current projects examine improving uptake and adherence of HIV pre-exposure prophylaxis in sexual and gender minority youth, increasing STI and HIV screening in primary care, and identifying patient, neighborhood, and clinic-based barriers to HIV and sexual health service delivery.
Dr. Won is the Human Factors Program Manager for the Center for Healthcare Quality and Analytics (CHQA), adjunct assistant professor for the Perelman School of Medicine and the School of Engineering at the University of Pennsylvania, and a senior fellow at the Center for Injury Research and Prevention.
As a bioengineer, Dr. Arbogast's research focuses on pediatric injury biomechanics, injury causation and the effectiveness of safety products for children with a concentration in the safety of children and youth in motor vehicle crashes as well as pediatric concussion.
Dr. Guevara is the principal investigator on research grants evaluating health inequities in early childhood development and behavioral problems. He utilizes community-based participatory clinical trials involving parent advocacy groups, community organizations, and government agencies to test the effects of psychosocial interventions designed to provide parents with resources and tools to improve the care of their children.
Dr. Grimberg investigates the growth hormone (GH)/insulin-like growth factor (IGF)-I axis and clinical issues related to child growth. Her recent research is focused on disparities in, and the decision-making related to, the medical management of children with short stature. She is fascinated by how differential societal pressures for tallness and the advent of an expensive therapeutic have transformed a fundamental aspect of pediatric healthcare.
Dr. McCormack investigates the intersection of neuroendocrinology and metabolism. Her translational research program involves two areas. The first involves studying those with genetic disorders, including primary mitochondrial diseases and Friedreich's ataxia, with characterized risk for diabetes mellitus. Second, Dr. McCormack focuses on brain disorders associated with excess weight gain, including brain tumor-related hypothalamic obesity syndrome and idiopathic intracranial hypertension.
Dr. Shalem’s research focuses on translational target discovery for a range of neurodegenerative diseases. He combines technology development of large-scale CRISPR-based perturbation screens with application of such technology together with additional genomic approaches.