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Results for T Regulatory Cells

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Neil D. Romberg, MD
Neil D. Romberg

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

E-mail:
rombergn [at] chop.edu
Kai Tan, PhD
Kai Tan

Dr. Tan uses experimental and computational approaches to study normal development and cancer. His laboratory is using the integrative approach to dissect the gene regulatory networks controlling embryonic hematopoiesis, T cell differentiation, and oncogenesis. He is also developing computational algorithms for constructing models of transcriptional regulatory and signaling networks by integrating multi-dimensional genomic, epigenomic, and transcriptomic datasets.

E-mail:
tank1 [at] chop.edu
Benjamin J. Samelson-Jones, MD, PhD
Benjamin J. Samelson-Jones

Dr. Samelson-Jones is a pediatric hematologist dedicated to improving the lives of children with bleeding and clotting disorders. His research focuses on gene therapy for hemophilia, the biochemical basis of coagulation, and the immune responses to hemophilia therapies.

E-mail:
samelsonjonesb [at] chop.edu
Stanley Stachelek, PhD
Stanley J. Stachelek

Dr. Stachelek's research interests are in the cellular and molecular mechanisms that control vasculature inflammation.

E-mail:
stachelek [at] chop.edu
Michael Silverman, MD, PhD
Michael Silverman

Dr. Silverman studies the fundamental aspects of early-life commensal microbes that influence immune system development and function. He discovered that the MHC-II E molecule prevents type 1 diabetes by shaping the intestinal microbiota early in life.

E-mail:
silvermam1 [at] chop.edu
Lan Lin, PhD
Lan Lin

Dr. Lin studies RNA modifications (a.k.a "epitranscriptomics") in human diseases, including cancer. She develops and applies high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications, including A-to-I RNA editing and m6A RNA methylation.

E-mail:
linlan [at] chop.edu
Daniel P. Kelly, MD
Daniel P. Kelly

Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.

E-mail:
dankelly [at] pennmedicine.upenn.edu
Pedro Gonzalez-Alegre, MD, PhD
Dr. Gonzalez-Alegre’s long-range research goal is to advance the application of precision medicine in the neurology clinic. His research focus revolves around genetic disorders that affect the brain, spanning from the diagnosis of novel genetic disease in the clinic to the identification of novel molecular targets using disease models and the design of early-phase human clinical trials.

Dr. Gonzalez-Alegre's long-range research goal is to advance the application of precision medicine in the neurology clinic. His research focus revolves around genetic disorders that affect the brain, spanning from the diagnosis of novel genetic disease in the clinic to the identification of novel molecular targets using disease models and the design of early-phase human clinical trials.

E-mail:
gonzalezap [at] chop.edu
Shaon Sengupta, MBBS, MPH
Shaon Sengupta

Dr. Sengupta is a neonatologist and physician scientist with a long-standing interest in lung health. She studies the mechanisms of circadian regulation of lung inflammation, injury, and repair; and the effect of early life exposures on development and function of pulmonary circadian networks in adulthood.

E-mail:
senguptas [at] chop.edu
Julie C. Fitzgerald, MD, PhD, MSCE
Julie C. Fitzgerald

Dr. Fitzgerald's research focuses on the impact of pediatric sepsis on renal dysfunction. She examines biomarkers that may be helpful in predicting renal dysfunction in septic acute kidney injury, and the impact of resuscitative therapies and pharmacometrics in sepsis on the development of sepsis-related renal dysfunction.

E-mail:
fitzgeraldj [at] chop.edu
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In this section

Filter By

  • Principal Investigator / Faculty (12)
  • Researcher / Lab Personnel (1)

Organizations

  • Department of Pediatrics (7)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (6)
  • Center for Computational and Genomic Medicine (5)
  • Department of Biomedical and Health Informatics (5)
  • Division of Infectious Diseases (5)
  • Center for Applied Genomics (4)
  • Center for Childhood Cancer Research (4)
  • Division of Allergy and Immunology (4)
  • Division of Oncology (4)
  • Blobel Laboratory (3)
  • Cell and Gene Therapy Collaborative (3)
  • Department of Pathology and Laboratory Medicine (3)
  • Department of Surgery (3)
  • Division of Hematology (3)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Mitochondrial and Epigenomic Medicine (2)
  • Center for Spatial and Functional Genomics (2)
  • Division of Emergency Medicine (2)
  • Immune Dysregulation Program (2)
  • Mitochondrial Medicine (2)
  • Office of Academic Training and Outreach Programs (2)
  • PennCHOP Microbiome Program (2)
  • Anderson Laboratory (1)
  • Bernt Laboratory (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Injury Research and Prevention (1)
  • Clinical Vector Core (1)
  • Department of Anesthesiology and Critical Care Medicine (1)
  • Department of Radiology (1)
  • Division of Cardiology (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Neonatology (1)
  • Division of Nephrology (1)
  • Division of Neurology (1)
  • Division of Neurosurgery (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Protective Immunity (1)
  • Division of Rheumatology (1)
  • Division of Transplant Immunology (1)
  • Epilepsy NeuroGenetics Initiative (ENGIN) (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Food Allergy Center (1)
  • George Laboratory (1)
  • Institutional Review Board (1)
  • Liao Laboratory (1)
  • Lifespan Brain Institute (1)
  • Lin Laboratory (1)
  • Mir Laboratory (1)
  • Nah-Cederquist Laboratory (1)
  • Office of Research Compliance (1)
  • Office of Research Safety (1)
  • Oliver Laboratory (1)
  • Pediatric Center of Excellence in Nephrology (1)
  • PolicyLab (1)
  • Roberts Individualized Medical Genetics Center (1)
  • Romberg Laboratory (1)
  • Silverman Laboratory (1)
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