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Results for Single Cell Analysis

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1 - 10 of 56

Kai Tan, PhD
Kai Tan

Dr. Tan uses experimental and computational approaches to study normal development and cancer. His laboratory is using the integrative approach to dissect the gene regulatory networks controlling embryonic hematopoiesis, T cell differentiation, and oncogenesis. He is also developing computational algorithms for constructing models of transcriptional regulatory and signaling networks by integrating multi-dimensional genomic, epigenomic, and transcriptomic datasets.

E-mail:
tank1 [at] chop.edu
Liming Pei, PhD
Liming Pei

Dr. Pei's research aims to understand the molecular underpinnings of cardiac remodeling associated with cardiomyopathy and heart failure. He is particularly interested in two areas of cardiac remodeling: metabolic reprogramming, and secretion of heart-derived hormones to communicate with other organs.

E-mail:
peil [at] chop.edu
Eric D. Marsh, MD, PhD
Eric D. Marsh

Dr. Marsh's research program focuses on understanding how changes in brain development lead to epilepsy, intellectual disability, and autism. He combines molecular and physiological tools in mouse models to ask questions about the interaction of normal development with single gene mutations to determine how the brain responds to perturbations in development.

E-mail:
marshe [at] chop.edu
Christopher J. Cardinale, MD, PhD
Christopher J. Cardinale

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:
cardinalec [at] chop.edu
Kristina A. Cole, MD, PhD
Kristina A. Cole

Dr. Cole is a pediatric neuro-oncologist who has dedicated her career to translational and clinical research, combining her expertise in molecular pathology, cancer genomics, and developmental therapeutics to identify novel treatments for children with cancer.

E-mail:
colek [at] chop.edu
Wanding Zhou, PhD
Wanding Zhou

Dr. Zhou’s outstanding research interests include mitosis-coupled DNA methylation drift and inference of cell-type-specific epigenetic signals. He developed multiple computational tools for analyzing DNA methylation data and has actively contributed to cancer genomics data analysis.

E-mail:
zhouw3 [at] chop.edu

In the News: Top Pediatrics Program for Medical Schools, First-of-Its-Kind Gene Therapy Trial, Novel Computational Tool

Published on
May 26, 2023
in Cornerstone Blog
In the News: Top Pediatrics Program for Medical Schools, Rare Disease Research, Novel Tool
In this week’s news roundup, CHOP’s Department of Pediatrics ranked No 1. in U.S. News & World Report’s ‘Best Pediatrics Programs’ for medical schools.

Single Cell Technology Core Data Analysis Services

Published on
Mar 8, 2023
in Announcements
Single Cell Technology Core Data Analysis Services
The Single Cell Technology Core provides data analysis services to support the CHOP/UPenn research community.

In the News: ASCI Membership, STAT Madness, Brain Chart, Single Ventricle Research Fund

Published on
Mar 3, 2023
in Cornerstone Blog
In the News: ASCI Membership, STAT Madness, Brain Chart
In this news roundup, learn about the achievements of CHOP researchers from societal inductions to grant- and grand-prize recipients.

Snapshot Science: How Can Single-cell Sequencing Overcome Computational Limitations?

Published on
Jan 30, 2023
in Cornerstone Blog
Researchers Develop Single-cell Multimodal Deep Clustering Software Tool
New software uses machine learning to analyze data about a single cell’s multiple characteristics.
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In this section

Filter By

  • Principal Investigator / Faculty (6)

Organizations

  • Department of Biomedical and Health Informatics (12)
  • Center for Applied Genomics (8)
  • Center for Computational and Genomic Medicine (7)
  • Department of Pathology and Laboratory Medicine (6)
  • Department of Pediatrics (6)
  • Center for Childhood Cancer Research (5)
  • Center for Injury Research and Prevention (5)
  • Division of Oncology (4)
  • Center for Single Cell Biology (3)
  • Clinical Futures (3)
  • Division of Allergy and Immunology (3)
  • Division of Orthopaedic Surgery (3)
  • Mitochondrial Medicine (3)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (3)
  • Cancer Immunotherapy (CAR-T) (2)
  • Center for Applied Genomics Laboratory (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Mitochondrial and Epigenomic Medicine (2)
  • Division of Neonatology (2)
  • Division of Pulmonary and Sleep Medicine (2)
  • PolicyLab (2)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (2)
  • Brain-Gene-Development Lab (1)
  • Center for Autism Research (1)
  • Center for Pediatric Heart Valve Disorders (1)
  • Center for Spatial and Functional Genomics (1)
  • Children’s Oncology Group (1)
  • CHOP Cardiovascular Institute (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Congenital Hyperinsulinism Research Laboratory (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Department of Radiology (1)
  • Department of Surgery (1)
  • Division of Adolescent Medicine (1)
  • Division of Cardiology (1)
  • Division of Emergency Medicine (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of General Pediatrics (1)
  • Division of Human Genetics (1)
  • Division of Nephrology (1)
  • Division of Neurology (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Rheumatology (1)
  • eMERGE (1)
  • Institutional Review Board (1)
  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
  • Lefebvre Laboratory (1)
  • Lifespan Brain Institute (1)
  • Minds Matter Concussion Program (1)
  • Pei Laboratory (1)
  • Roberts Individualized Medical Genetics Center (1)
  • Romberg Laboratory (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
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