Dr. Alexander-Bloch investigates normal brain development and the altered developmental trajectories that lead to mental illness. His multi-disciplinary research integrates brain imaging, genomics and clinical information.
Dr. Roberts investigates brain-wave scanning with magnetoencephalography (MEG) and works to identify biomarkers for neuropsychiatric disorders like autism. Those biomarkers are for diagnosis, prognosis, stratification, and response monitoring as well as substrate identification for targeted therapy. Putting the "bio" into biomarkers is a major emphasis of Dr. Roberts' research, for which he uses advanced diffusion magnetic resonance imaging (MRI) and edited spectroscopy.
Dr. Anderson’s research interests focus on the molecular and cellular mechanisms that govern the development of the mammalian forebrain. In his research on the development of the cerebral cortex, he is particularly interested in understanding the molecular underpinnings behind the fate determination and axon targeting of subclasses of GABAergic interneurons implicated in the neuropathology of schizophrenia.
Dr. Edgar has more than 25 years of experience using non-invasive imaging to study brain function and structure in psychiatric and neurological patient populations. His most recent research focuses on studying brain structure and function maturation processes.
The Anderson Laboratory investigates the molecular and cellular mechanisms governing the development of the mammalian forebrain in relation to neuropsychiatric disease. The lab has a particular research interest on the fate determination of key subclasses of cortical inhibitory interneurons.
In advancing intellectual and developmental disabilities (IDD) research for more than 29 years, the Intellectual and Developmental Disabilities Research Center (IDDRC) wholeheartedly embraces today’s novel concepts and technologies to discover the causes of IDD and uses this knowledge to improve outcomes for affected people.
Where Discovery Leads is a multimedia storytelling project that delves into key research themes at CHOP Research Institute. This is part one of a three-part series that focuses on novel diagnostic tools and approaches being developed under the leadership of the Center for Autism Research at CHOP. See part 2 and part 3 of the series.