Results for Protein Secretion

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Joseph W. St. Geme, III, MD
Joseph W. St. Geme

Dr. St. Geme's research focuses on bacterial pathogenesis, with an emphasis on defining the molecular and cellular determinants of Haemophilus influenzae and Kingella kingae disease.

E-mail:
stgemeIIIj [at] chop.edu
Charles A. Stanley, MD
Charles A. Stanley Headshot

Dr. Stanley’s lab has identified many of the genes and syndromes associated with congenital hyperinsulinism including ABCC8, GCK, GLUD1, and Turner and Beckwith syndromes. Working with clinical and rodent model studies, his lab team has identified distinctive phenotypes of these disorders, including diazoxide unresponsiveness, leucine sensitivity, and protein sensitivity. Dr. Stanley continues to seek new diagnostic and treatment paradigms for infants with acquired and genetic disorders of hyperinsulinism.

E-mail:
stanleyc [at] chop.edu

In The News: March of Dimes Prize, Immunotherapy, CHOP CARES, MIS-C, PCORI Grant

Published on
Feb 4, 2022
in Cornerstone Blog
In the News
Learn about novel findings neuroblastoma, MIS-C, and more in this week's roundup of research news.

Snapshot Science: Does a New Method Tackle the NMR Challenge of Large Proteins?

Published on
Feb 22, 2021
in Cornerstone Blog
New Magnetic Resonance Method to Study Drug Targets
Dr. Nikolaos Sgourakis led a group a researchers to develop a game-changing new method for nuclear magnetic resonance data analysis.

Nose vs. Lungs: Study Compares SARS-CoV-2 Concordance in Upper and Lower Respiratory Tracts

Published on
Jul 20, 2020
in Cornerstone Blog
COVID Confirm
Audrey Odom John, MD, PhD, is assessing concordance of SARS-CoV-2 in upper and lower respiratory tracts of children undergoing airway procedures.

Physician-in-Chief Cultivates Sense of Wonder Inspired by His Dad

Published on
Jun 21, 2020
in Cornerstone Blog
Dr. St. Geme with his father
Dr. St. Geme builds upon his father’s legacy to advance child health with his own research contributions and a focus on holistic care.

Grant Awarded to Study Gene Therapy for Disorders With Severe Brain Disease

Published on
Dec 4, 2019
in Cornerstone Blog
John Wolfe, VMD, PhD, is studying gene therapy methods to correct the brain disease of lysosomal storage disorders.
John Wolfe, VMD, PhD, receives grant to study gene therapy treatment for lysosomal storage disorders with severe disease of the brain.

In the Gut: Therapeutic Discovery in the Microbiome

Published on
Nov 21, 2018
in Cornerstone Blog
microbiome
Scientists from the PennCHOP Microbiome Program shared new developments in knowledge of the microbiome at their Fifth Annual Symposium.

In the News: New Rare Disease, FA Woodstock, Bioengineering, and Protecting Toddlers from Child Abuse

Published on
Jul 29, 2016
in Cornerstone Blog
CHOP Research In the News
Welcome back to another weekly edition of our roundup of research news from The Children's Hospital of Philadelphia! One of the things that is so exciting about research at CHOP is that our researchers are working to improve the health and lives of children in such a broad range of ways.

Scientists Reveal New Mechanism Adenovirus Uses to Sabotage Immune System

Published on
Jun 30, 2016
in Cornerstone Blog
Adenovirus, a common human virus that usually affects the lungs and causes respiratory tract infections, is an old friend to virologists. They have long studied how this virus interacts with host cells to understand cellular processes and reveal key regulators of cellular functions.
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