Results for Primary Immunological Diseases

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

Dr. Bailis aims to understand how metabolism underlies immunology and disease, by controlling the biochemistry of cells and tissues. His lab does so using in vitro and in vivo CRISPR engineering of primary human and mouse immune cells, with the goal of developing diet and metabolite based therapies.

Dr. Douglas has extensive laboratory experience investigating the cellular immunology of HIV/AIDS, primary immune deficiency diseases, and cellular immunopathologies. In addition, he has had significant involvement in studies related to immunological interactions.

Dr. Vella is an assistant professor of Pediatrics at Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine with a primary research focus on T follicular helper cells (Tfh), chronic infections, and vaccine readiness.

Dr. Ren's primary research focus is to develop better methods to assess lung disease in infants and young children using advanced pulmonary function testing and imaging.