Dr. Levine has an active laboratory research program that complements and extends his clinical studies. He has identified the molecular basis of several inherited disorders of mineral metabolism. His research interests extend to the molecular basis for embryological development of the parathyroid glands.
Dr. Rand's research interests include clinical studies of biliary atresia and studies of immunization, immune suppression, and long-term outcome after transplantation. Her basic science interests in liver development and fibrosis are carried out as collaborations with scientists who utilize the liver tissue bank.
Dr. Mascarenhas is director of the Nutrition Support Service, section chief of nutrition in the Division of Gastroenterology and Nutrition, medical director of the Clinical Nutrition Department, and director of the Integrative Health Program. Her research interests involve 22q deletion syndrome, cystic fibrosis, nutrition, and integrative medicine.
Dr. Tasian and his research team use an epidemiologic framework, including randomized trials and multi-institutional observational studies, to examine the etiology of kidney stone disease and the comparative effectiveness of surgical interventions. He also employs machine learning of complex data to improve diagnosis, risk stratification, and prediction of treatment response for children and adults with benign urologic disease.
Dr. Stallings is working on intervention trials involving three chronic diseases with nutrition-related abnormalities resulting in meaningful adverse outcomes: cystic fibrosis (new drugs), sickle cell disease (vitamin A) and chronic pancreatitis (enzyme replacement drug).
Dr. Zemel's overall research program aims to improve the understanding of lifelong health and how it relates to childhood antecedents of physical growth and maturation, body composition, population ancestry/genetics, and lifestyle factors. Such insight has practical implications for disease prevention and lifelong wellness, as well as broader scientific implications for understanding human plasticity and evolution.
Dr. Xanthopoulos's research focuses on the development, implementation, and adherence to medical and lifestyle interventions, including non-invasive ventilation (CPAP/BPAP), eating habits, physical activity, and sleep. She has a particular interest in the interactions among behavioral, lifestyle, psychosocial and physiologic factors as they relate to health and neurobehavioral functioning and quality of life in youth and families.
Dr. Zackular's research is focused on understanding how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease. His recent efforts center on understanding how the important nosocomial pathogen, Clostridium difficile, interacts with resident gut microbiota during infection and how interspecies cross-talk impacts growth, behavior, and virulence of this pathogen.
Dr. Loomes' research is focused on clinical and translational studies in pediatric liver disease. She works with National Institutes of Health-funded national consortia to conduct studies investigating the etiology and treatment for rare pediatric liver diseases including biliary atresia, Alagille syndrome, and others. Dr. Loomes also collaborates with other investigators at Children’s Hospital of Philadelphia to investigate genetic causes of pediatric liver disease.