Dr. Nader is an assistant professor in the Department of Pathology and Laboratory Medicine at CHOP. His research topics are focused on the nuclear mechano-sensing of cells that grow and move within dense microenvironments such as tumor microenvironment, interstitial space, or densely packed tissue.
Dr. Kelly’s research career began with deciphering the genetic basis of inborn errors in metabolism in children, followed by a series of breakthrough discoveries relevant to the diagnosis and treatment of common forms of heart failure in the general population.
Dr. Sgourakis’ research focuses on understanding the intricate molecular mechanisms that determine the vast repertoire of peptide antigens displayed by the proteins of the Major Histocompatibility Complex for immune surveillance by T cells and Natural Killer cells.
The Children’s Hospital of Philadelphia Research Institute’s Office of Academic Training and Outreach Programs announced the selection of two new Research Administration fellows. Katherine Yang-Iott and Danika Johnston, PhD.
Bookended by references to the 1980s and 1990s — in the form of an iconic U.S. Navy commercial and a discussion of the 1991 measles outbreak in Philadelphia — the 2015 CHOP Research Institute Scientific Symposium offered a snapshot of the inspirational work going on at CHOP every day.
The Mechanistic Molecular Immunology Lab integrates cutting-edge structural biology and biochemistry tools with functional immunoassays to understand the molecular basis of immune responses to viral infections and tumors, with an emphasis on the development of novel protein-based therapeutics.
Identifying and characterizing the cellular and molecular mechanisms regulating skeletal development, growth, and morphogenesis and developing new cell- or gene-based tools to treat and correct pediatric skeletal disorders.