Dr. Tunç is a computational scientist investigating the application of machine learning and statistical data analysis in various domains such as digital phenotyping, nature of psychopathology, and neuroimaging. He participates in studies using normative, developmental, and clinical samples to parse heterogeneity in psychiatric disorders by developing novel computational techniques.
Dr. Tsui's research interests include clinical informatics, natural language processing, artificial intelligence and machine learning, population informatics, data science, signal processing, mobile healthcare, and large real-time clinical production systems. He's published over 100 peer-reviewed papers.
Dr. Hakonarson is director of the Center for Applied Genomics and professor of Pediatrics at the Perelman School of Medicine, University of Pennsylvania. He leads a $40 million commitment from Children’s Hospital of Philadelphia to genomically characterize approximately 100,000 children, an initiative that has gained nationwide attention in the Wall Street Journal, New York Times, Time Magazine, Nature, and Science.
Using translational approaches that encompass genomic studies, biomarker development, disease modeling, natural history studies, and clinical trials, Dr. Vanderver seeks to improve the quality of life and lifespan of individuals living with leukodystrophies or heritable disorder of myelin. She leads the Leukodystrophy Center of Excellence at Children's Hospital of Philadelphia.
Dr. Bell, chief of the Division of General Pediatrics, has research expertise in areas including computerized clinical decision support to improve the quality of care; epidemiology, management and treatment of common pediatric infectious diseases; the use of primary care practice-based research networks for clinical research; and quality improvement through the use of clinical pathways.
Dr. Sgourakis’ research focuses on understanding the intricate molecular mechanisms that determine the vast repertoire of peptide antigens displayed by the proteins of the Major Histocompatibility Complex for immune surveillance by T cells and Natural Killer cells.
Dr. Muhly is a clinical investigator within the Division of Anesthesiology. His areas of investigation include pain management in pediatric patients presenting for complex surgical interventions and the application of quality improvement methodology to improve the perioperative care of children.
Dr. Masino and his team research the application and development of machine learning methods to inform basic scientific discovery and the creation of predictive analytic models for personal health and clinical decision support.
Dr. Zhou’s outstanding research interests include mitosis-coupled DNA methylation drift and inference of cell-type-specific epigenetic signals. He developed multiple computational tools for analyzing DNA methylation data and has actively contributed to cancer genomics data analysis.