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Results for Molecular Biology

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1 - 10 of 295

Michael S. Marks, PhD
Michael S. Marks

Dr. Marks investigates the molecular mechanisms underlying the formation of cell type-specific lysosome-related organelles; the assembly, delivery and function of their contents; and how these processes are impacted by genetic diseases.

E-mail:
marksms [at] chop.edu
Beverly L. Davidson, PhD
Photo of Beverly L. Davidson, PhD

Dr. Davidson works to understand the molecular basis of childhood onset neurodegenerative diseases and the development of gene and small molecule therapies for treatment. She also focuses on how noncoding RNAs participate in neural development and neurodegenerative disease processes, and how they can be harnessed for therapies.

E-mail:
davidsonbl [at] chop.edu
Jeffrey D. Roizen, MD, PhD, FAAP
Jeffrey D. Roizen

Dr. Roizen's research program aims to understand non-calciometabolic effects of vitamin D and to use this understanding to design new therapeutic approaches to common diseases such as sarcopenia and obesity.

E-mail:
roizenj [at] chop.edu
Yi Xing, PhD
Yi Xing

Dr. Xing is the Executive Director of the Department of Biomedical and Health Informatics, the Francis West Lewis Chair and director of the Center for Computational and Genomic Medicine at CHOP, and professor of Pathology and Laboratory Medicine at the University of Pennsylvania. His research focuses on computational biology and genomics of RNA processing and regulation.

E-mail:
xingyi [at] chop.edu
Itzhak Nissim, PhD

Dr. Nissim is a biochemist and a pioneer in the application of stable isotopes, mass spectrometry, and nuclear magnetic resonance to study metabolome and fluxome and their coupling to genome in normal and disease states. His long-standing interest focuses on understanding the cause, mechanisms, and outcome of metabolic disorders.

E-mail:
nissim [at] chop.edu
Lan Lin, PhD
Lan Lin

Dr. Lin studies RNA modifications (a.k.a "epitranscriptomics") in human diseases, including cancer. She develops and applies high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications, including A-to-I RNA editing and m6A RNA methylation.

E-mail:
linlan [at] chop.edu
Andrew D. Wells, PhD
Andrew D. Wells

Dr. Wells studies the genetic, epigenetic, and transcriptional mechanisms that control T lymphocyte immunity and tolerance.

E-mail:
wellsa [at] chop.edu
Eiko Nakamaru-Ogiso, PhD
Eiko Nakamaru-Ogiso
E-mail:
ogisoe [at] chop.edu
Ian M. Cambell, MD, PhD
Ian M. Campbell

Dr. Campbell is interested in approaches to improve diagnosis of children with rare genetic diseases. He also focuses on better understanding of the full spectrum of symptoms associated with genetic diseases as well as discovering new diseases.

E-mail:
campbellim [at] chop.edu
Beverly S. Emanuel, PhD
Beverly S. Emanuel Headshot

Dr. Emanuel investigates diseases caused by abnormalities of human chromosome 22. These include the most common microdeletion syndrome, 22q11.2 deletion syndrome, and the most common recurrent constitutional translocation in humans, the t(11;22). Her efforts include discerning the mechanisms involved in generating the deletion and translocation as well as looking for modifiers of the phenotype in individuals with the deletion syndrome.

E-mail:
emanuel [at] chop.edu
1 - 10 of 295

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In this section

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  • Principal Investigator / Faculty (101)
  • Researcher / Lab Personnel (12)
  • Research Administration (6)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (23)
  • Center for Computational and Genomic Medicine (19)
  • Department of Pediatrics (19)
  • Department of Pathology and Laboratory Medicine (16)
  • Center for Applied Genomics (14)
  • Center for Childhood Cancer Research (14)
  • Department of Biomedical and Health Informatics (11)
  • Center for Injury Research and Prevention (10)
  • Division of Hematology (10)
  • PolicyLab (9)
  • Center for Autism Research (7)
  • Division of Endocrinology and Diabetes (7)
  • Division of Human Genetics (7)
  • Division of Neonatology (7)
  • Mitochondrial Medicine (7)
  • Center for Mitochondrial and Epigenomic Medicine (6)
  • Division of Neurology (6)
  • Division of Oncology (6)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (6)
  • Roberts Individualized Medical Genetics Center (6)
  • Anderson Laboratory (5)
  • Center for Data-Driven Discovery in Biomedicine (5)
  • Clinical Futures (5)
  • Lifespan Brain Institute (5)
  • Department of Anesthesiology and Critical Care Medicine (4)
  • Department of Surgery (4)
  • Division of Allergy and Immunology (4)
  • Division of Cancer Pathobiology (4)
  • Developmental Biology Research Affinity Group (3)
  • Division of Gastroenterology, Hepatology, and Nutrition (3)
  • Division of Nephrology (3)
  • Office of Academic Training and Outreach Programs (3)
  • Pediatric Center of Excellence in Nephrology (3)
  • Center for Spatial and Functional Genomics (2)
  • Center for Violence Prevention (2)
  • Children’s Oncology Group (2)
  • Comprehensive Bone Marrow Failure Center (2)
  • Division of Infectious Diseases (2)
  • Division of Protective Immunity (2)
  • Division of Rheumatology (2)
  • Hamilton Laboratory (2)
  • Mir Laboratory (2)
  • Penn-CHOP Kidney Innovation Center (2)
  • PennCHOP Microbiome Program (2)
  • Research Vector Core (2)
  • Thyroid Center (2)
  • Advancement of Hyperinsulinism Care and Research (1)
  • Ahrens-Nicklas Laboratory (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Craniofacial Innovation (1)
  • Center for the Investigation of Factor FVIII Immunogenicity (1)
  • CHOP Postdoctoral Alliance (1)
  • Clinical Research Support Office (1)
  • Davidson Laboratory (1)
  • Department of Radiology (1)
  • Division of Cardiology (1)
  • Division of Cell Pathology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • Henrickson Laboratory (1)
  • Heuckeroth Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
  • Jolley Laboratory (1)
  • Levine Laboratory (1)
  • Liao Laboratory (1)
  • Lin Laboratory (1)
  • Lurie Family Foundations MEG Imaging Center (1)
  • Mechanistic Molecular Immunology Lab (1)
  • Minds Matter Concussion Program (1)
  • Nah-Cederquist Laboratory (1)
  • PEDSnet (1)
  • Pei Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Project Management Office (1)
  • Sengupta Laboratory (1)
  • Shalem Laboratory (1)
  • Song Laboratory (1)
  • Spatial and Functional Genomics Research Affinity Group (1)
  • St. Geme Laboratory (1)
  • Stress Neurobiology Program (1)
  • Tasian Laboratory (1)
  • Thomas-Tikhonenko Laboratory (1)
  • Wallace Laboratory (1)

In this section

Filter By

  • Principal Investigator / Faculty (101)
  • Researcher / Lab Personnel (12)
  • Research Administration (6)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (23)
  • Center for Computational and Genomic Medicine (19)
  • Department of Pediatrics (19)
  • Department of Pathology and Laboratory Medicine (16)
  • Center for Applied Genomics (14)
  • Center for Childhood Cancer Research (14)
  • Department of Biomedical and Health Informatics (11)
  • Center for Injury Research and Prevention (10)
  • Division of Hematology (10)
  • PolicyLab (9)
  • Center for Autism Research (7)
  • Division of Endocrinology and Diabetes (7)
  • Division of Human Genetics (7)
  • Division of Neonatology (7)
  • Mitochondrial Medicine (7)
  • Center for Mitochondrial and Epigenomic Medicine (6)
  • Division of Neurology (6)
  • Division of Oncology (6)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (6)
  • Roberts Individualized Medical Genetics Center (6)
  • Anderson Laboratory (5)
  • Center for Data-Driven Discovery in Biomedicine (5)
  • Clinical Futures (5)
  • Lifespan Brain Institute (5)
  • Department of Anesthesiology and Critical Care Medicine (4)
  • Department of Surgery (4)
  • Division of Allergy and Immunology (4)
  • Division of Cancer Pathobiology (4)
  • Developmental Biology Research Affinity Group (3)
  • Division of Gastroenterology, Hepatology, and Nutrition (3)
  • Division of Nephrology (3)
  • Office of Academic Training and Outreach Programs (3)
  • Pediatric Center of Excellence in Nephrology (3)
  • Center for Spatial and Functional Genomics (2)
  • Center for Violence Prevention (2)
  • Children’s Oncology Group (2)
  • Comprehensive Bone Marrow Failure Center (2)
  • Division of Infectious Diseases (2)
  • Division of Protective Immunity (2)
  • Division of Rheumatology (2)
  • Hamilton Laboratory (2)
  • Mir Laboratory (2)
  • Penn-CHOP Kidney Innovation Center (2)
  • PennCHOP Microbiome Program (2)
  • Research Vector Core (2)
  • Thyroid Center (2)
  • Advancement of Hyperinsulinism Care and Research (1)
  • Ahrens-Nicklas Laboratory (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Craniofacial Innovation (1)
  • Center for the Investigation of Factor FVIII Immunogenicity (1)
  • CHOP Postdoctoral Alliance (1)
  • Clinical Research Support Office (1)
  • Davidson Laboratory (1)
  • Department of Radiology (1)
  • Division of Cardiology (1)
  • Division of Cell Pathology (1)
  • Division of Developmental and Behavioral Pediatrics (1)
  • Division of Ophthalmology (1)
  • Division of Orthopaedic Surgery (1)
  • Division of Plastic, Reconstructive and Oral Surgery (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Friedreich’s Ataxia Center of Excellence (1)
  • Henrickson Laboratory (1)
  • Heuckeroth Laboratory (1)
  • Inflammatory Bowel Disease Center (1)
  • Jill and Mark Fishman Center for Lymphatic Disorders (1)
  • Jolley Laboratory (1)
  • Levine Laboratory (1)
  • Liao Laboratory (1)
  • Lin Laboratory (1)
  • Lurie Family Foundations MEG Imaging Center (1)
  • Mechanistic Molecular Immunology Lab (1)
  • Minds Matter Concussion Program (1)
  • Nah-Cederquist Laboratory (1)
  • PEDSnet (1)
  • Pei Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research Project Management Office (1)
  • Sengupta Laboratory (1)
  • Shalem Laboratory (1)
  • Song Laboratory (1)
  • Spatial and Functional Genomics Research Affinity Group (1)
  • St. Geme Laboratory (1)
  • Stress Neurobiology Program (1)
  • Tasian Laboratory (1)
  • Thomas-Tikhonenko Laboratory (1)
  • Wallace Laboratory (1)
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