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Results for Mitochondrial Dysfunction

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Snapshot Science: Could Improved Mitochondrial Function Affect Pediatric Neurodegeneration?

Published on
Oct 21, 2021
in Cornerstone Blog
TBCK-patient derived fibroblasts
Findings support lysosomal acidification strategies for pediatric neurodegenerative disorders with impaired mitochondrial quality control.

Researchers Explore Connection Between Mitochondrial Function and Schizophrenia in 22q11DS

Published on
Jul 19, 2021
in Cornerstone Blog
Mitochondrial Function and Schizophrenia in 22q11DS
CHOP and Penn researchers find connection between mitochondrial function and mental illness in patients with a rare genetic disorder.

In the News: Quantifying Concussions, Vitamins for Mitochondrial Disease, Autism and Police Encounters, Using Smartphones, Doug Wallace

Published on
Jan 26, 2018
in Cornerstone Blog
CHOP Research In the News
From studying smartphone use to sports-related injuries, don't miss this week's roundup of news updates from CHOP researchers.

Altered Mitochondria Associated with Increased Autism Risk

Published on
Aug 23, 2017
in Press Releases
CHOP Scientist: Ancient Mitochondrial DNA Genetic Patterns May Play Role in this Neurodevelopmental Condition

Wilson Laboratory

Wilson Lab

The Wilson Lab studies the inherited neuro- and cardio-degenerative mitochondrial disorder, Friedreich ataxia (FA). The lab also constructed the first random shRNA-expressing libraries and is using these libraries for drug discovery in a variety of disorders.

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Organizations

  • (-) Division of Neurology (5)
  • (-) Department of Pathology and Laboratory Medicine (4)
  • (-) Department of Child and Adolescent Psychiatry and Behavioral Sciences (3)
  • (-) Center for Applied Genomics (2)
  • (-) Center for Autism Research (1)
  • Center for Mitochondrial and Epigenomic Medicine (12)
  • Mitochondrial Medicine (9)
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  • Friedreich’s Ataxia Center of Excellence (3)
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  • Minds Matter Concussion Program (1)
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  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)

In this section

Organizations

  • Mitochondrial Medicine (9)
  • Center for Injury Research and Prevention (6)
  • Division of Neurology (5)
  • Center for Childhood Cancer Research (4)
  • Department of Pathology and Laboratory Medicine (4)
  • Department of Pediatrics (4)
  • Department of Child and Adolescent Psychiatry and Behavioral Sciences (3)
  • Division of Infectious Diseases (3)
  • Friedreich’s Ataxia Center of Excellence (3)
  • PolicyLab (3)
  • Anderson Laboratory (2)
  • Center for Applied Genomics (2)
  • Division of Human Genetics (2)
  • Division of Oncology (2)
  • Cancer Immunotherapy (CAR-T) (1)
  • Center for Autism Research (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Spatial and Functional Genomics (1)
  • Clinical Futures (1)
  • Division of Allergy and Immunology (1)
  • Division of Endocrinology and Diabetes (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Protective Immunity (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Division of Rheumatology (1)
  • Lifespan Brain Institute (1)
  • mHealth Research Affinity Group (1)
  • Minds Matter Concussion Program (1)
  • Ortiz-Gonzalez Laboratory (1)
  • PEDSnet (1)
  • Sleep Center (1)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (1)
  • (-) Center for Mitochondrial and Epigenomic Medicine (12)
  • (-) Department of Anesthesiology and Critical Care Medicine (3)
  • (-) Center for Data-Driven Discovery in Biomedicine (2)
  • (-) Department of Biomedical and Health Informatics (2)
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