Certain defects in the way the mitochondria work may lead to diabetes, and the ways our bodies adapt to high blood sugars share many features with the ways our bodies respond to mitochondrial disease.
The Wilson Lab studies the inherited neuro- and cardio-degenerative mitochondrial disorder, Friedreich ataxia (FA). The lab also constructed the first random shRNA-expressing libraries and is using these libraries for drug discovery in a variety of disorders.
