Results for Mitochondrial Dysfunction

With a grant from the Gates Foundation, CHOP researchers are working to determine the importance of mitochondria DNA variation in COVID-19 severity.

A U.S. Department of Defense grant will support CHOP researchers in their study of noninvasive methods to diagnose mitochondrial diseases.

Findings support lysosomal acidification strategies for pediatric neurodegenerative disorders with impaired mitochondrial quality control.

CHOP and Penn researchers find connection between mitochondrial function and mental illness in patients with a rare genetic disorder.

Researchers at CHOP collaborated with NASA and other institutions to determine possible mechanisms behind the health effects of spaceflight.

From studying smartphone use to sports-related injuries, don't miss this week's roundup of news updates from CHOP researchers.

"There is a great sense of community and interconnectedness among the folks who are here," said an attendee of the 10th Annual Friedreich's Ataxia Symposium.

Differences in mitochondrial function are a major factor in understanding the origins of autism spectrum disorders (ASD), according to a new study led by Douglas Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine at Children's Hospital of Philadelphia, that points way back to genetic vulnerabilities accumulated during ancient human migrations.

Today, the prevalence of ASD is estimated

CHOP Scientist: Ancient Mitochondrial DNA Genetic Patterns May Play Role in this Neurodevelopmental Condition

Although October is just ending, we're already looking ahead to the New Year in this week's installment of In the News.