Results for Innate and Adaptive Immune Systems

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Alix E. Seif, MD, MPH
Alix E. Seif

Dr. Seif's research centers on manipulating the human innate and immune systems to treat children with acute lymphoblastic leukemia (ALL). The long-term goal of her research is to identify innate and adaptive immune mechanisms that can be used to treat pediatric ALL more effectively, and with less toxicity, than existing therapies.

E-mail:
seifa [at] email.chop.edu
View Alix E. Seif's Profile
Craig H. Bassing, PhD
Craig H. Bassing

Dr. Bassing's research program focuses on the genetic, epigenetic, and biochemical mechanisms by which mammals develop their immune systems while suppressing autoimmunity and genomic aberrations that cause leukemia or lymphoma.

E-mail:
bassing [at] email.chop.edu
View Craig H. Bassing's Profile

New Gene Variants Found in Very Early Onset Inflammatory Bowel Disease

Published on
Sep 10, 2015
in Cornerstone Blog
Melding together genomics technology, disease patterns, immunology, and microbiology, physician-scientists at The Children’s Hospital of Philadelphia are finding new and individualized therapies for patients with very early onset inflammatory bowel disease.

Seif Laboratory

Seif Laboratory

The Seif Lab is focused on manipulating the human innate and immune systems to treat children with acute lymphoblastic leukemia (ALL). The lab’s long-term goal of the research conducted is to identify innate and adaptive immune mechanisms that can be used to treat pediatric ALL more effectively, and with less toxicity, than existing therapies.

Bassing Laboratory

Bassing Lab

The goals of research in the Bassing Lab are to elucidate the genetic, epigenetic, and biochemical mechanisms by which mammals develop their immune systems while suppressing autoimmunity and genomic aberrations that cause leukemia or lymphoma.

Division of Protective Immunity

Protective Immunity

Leveraging innovative experimental methodology, computational approaches, and molecular tools to better understand immune system development, immune response to microorganisms, and mucosal immunology.

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