Results for Genomic Data

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Dr. Hakonarson is director of the Center for Applied Genomics and professor of Pediatrics at the Perelman School of Medicine, University of Pennsylvania. He leads a $40 million commitment from Children’s Hospital of Philadelphia to genomically characterize approximately 100,000 children, an initiative that has gained nationwide attention in the Wall Street Journal, New York Times, Time Magazine, Nature, and Science.

E-mail:

hakonarson [at] chop.edu

Wanding Zhou, PhD

Dr. Zhou’s outstanding research interests include mitosis-coupled DNA methylation drift and inference of cell-type-specific epigenetic signals. He developed multiple computational tools for analyzing DNA methylation data and has actively contributed to cancer genomics data analysis.

E-mail:

zhouw3 [at] chop.edu

Yi Xing, PhD

Dr. Xing is the Executive Director of the Department of Biomedical and Health Informatics, the Francis West Lewis Chair and director of the Center for Computational and Genomic Medicine at CHOP, and professor of Pathology and Laboratory Medicine at the University of Pennsylvania. His research focuses on computational biology and genomics of RNA processing and regulation.

E-mail:

xingyi [at] chop.edu

Kai Wang, PhD

Dr. Wang's research focuses on the development of bioinformatics methods to improve the understanding of the genetic basis of human diseases, and the integration of electronic health records and genomic information to facilitate genomic medicine on scale.

E-mail:

wangk [at] chop.edu

Andrew D. Wells, PhD

Dr. Wells studies the genetic, epigenetic, and transcriptional mechanisms that control T lymphocyte immunity and tolerance.

E-mail:

wellsa [at] chop.edu

Ian M. Cambell, MD, PhD

Dr. Campbell is interested in approaches to improve diagnosis of children with rare genetic diseases. He also focuses on better understanding of the full spectrum of symptoms associated with genetic diseases as well as discovering new diseases.

E-mail:

campbellim [at] chop.edu

Yang Ding, MD

Dr. Ding is an attending physician with the Cancer Center at CHOP. As for her research, she works to discover oncogenic co-dependencies using genomics data with the goal to develop novel precision medicine techniques for children with cancer. She focuses on high-risk leukemias and computational biology.

E-mail:

dingy [at] chop.edu

Suzanne P. MacFarland, MD

Dr. MacFarland's research focuses on syndromes that predispose to cancer development in children and adolescents. She has initiated several individual and collaborative research projects, working in pediatric polyposis syndromes and Li-Fraumeni syndrome. She is uncovering novel genomic drivers of disease and identifying biomarkers of cancer onset and progression.

E-mail:

macfarlands [at] chop.edu

Aaron Alexander-Bloch, MD, PhD

Dr. Alexander-Bloch investigates normal brain development and the altered developmental trajectories that lead to mental illness. His multi-disciplinary research integrates brain imaging, genomics and clinical information.

E-mail:

alexanderba [at] chop.edu

Christopher J. Cardinale, MD, PhD

Dr. Cardinale's research is focused on understanding the mechanisms of gene expression and gene regulation in autoimmune diseases, including inflammatory bowel disease, type 1 diabetes, and systemic sclerosis. He uses data from large-scale genomic studies to identify disease-causing genetic variants and functionally explore the target genes of those variants.

E-mail:

cardinalec [at] chop.edu