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Results for Gene Silencing

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Beverly L. Davidson, PhD
Photo of Beverly L. Davidson, PhD

Dr. Davidson works to understand the molecular basis of childhood onset neurodegenerative diseases and the development of gene and small molecule therapies for treatment. She also focuses on how noncoding RNAs participate in neural development and neurodegenerative disease processes, and how they can be harnessed for therapies.

E-mail:
davidsonbl [at] chop.edu
Pedro Gonzalez-Alegre, MD, PhD
Dr. Gonzalez-Alegre’s long-range research goal is to advance the application of precision medicine in the neurology clinic. His research focus revolves around genetic disorders that affect the brain, spanning from the diagnosis of novel genetic disease in the clinic to the identification of novel molecular targets using disease models and the design of early-phase human clinical trials.

Dr. Gonzalez-Alegre's long-range research goal is to advance the application of precision medicine in the neurology clinic. His research focus revolves around genetic disorders that affect the brain, spanning from the diagnosis of novel genetic disease in the clinic to the identification of novel molecular targets using disease models and the design of early-phase human clinical trials.

E-mail:
gonzalezap [at] chop.edu
Alaa Narch
Alaa Narch

Alaa Narch is a research technician in the Wolpaw Lab investigating the activation and immuno-therapeutic potential of the cGAS-STING inflammation pathway.

E-mail:
narcha [at] chop.edu

In the News: Research Podcast, RWJF Award, Fetal Hemoglobin, CPAP Use

Published on
Aug 19, 2022
in Cornerstone Blog
In the News
In our latest news roundup, new findings on fetal hemoglobin, continuous positive airway pressure, and more.

In the News: Featured Research, Tonsillectomy, Gene Therapy, CAR T-Cell Therapy

Published on
Jun 24, 2022
in Cornerstone Blog
In the News
This week’s In the News features endocrinology research, news on gene therapy in blood disorders, CAR T-cell therapy, and more.

In the News: Autism and COVID, Telemedicine, Hemoglobin, Williams Syndrome, AYAs

Published on
Jun 10, 2022
in Cornerstone Blog
In the News
This week’s news roundup features discoveries related to COVID-19’s effect on adolescents, autism screening, telemedicine, and more.

Snapshot Science: How Did Researchers Resolve Adverse Symptoms that Emerged with AAV-based RNA Interference Strategies for Ataxia Therapy?

Published on
Oct 18, 2021
in Cornerstone Blog
Researchers Resolve Symptoms that Emerged with AAV-based RNAi for SCA1
Raymond G. Perelman Center for Cellular and Molecular Therapeutics team highlights that extended safety testing of AAV-based RNAi strategies is critical.

Snapshot Science: How Does the Overexpression of MN1 Cause Acute Myeloid Leukemia?

Published on
May 19, 2021
in Cornerstone Blog
How the Overexpression of MN1 Causes Acute Myeloid Leukemia
CHOP Researchers find the novel mechanistic link by which MNI causes acute myeloid leukemia.

In the News: Chromatin Rebuilding, Hemophilia Oral Treatment, Linking CVD and CKD, New Algorithm Detects Genetic Variants

Published on
Dec 13, 2019
in Cornerstone Blog
In the News
Learn about developments in chromatin rebuilding, novel hemophilia treatment, linking heart and kidney disease, and genetic sequencing.

LiBI Gathers Experts to Explore How Early Life Influences Neurodevelopment

Published on
Apr 12, 2019
in Cornerstone Blog
LiBI Symposium
LiBI, a unique collaborative effort, bridges the gap between pediatric and adult research to learn how brain and behavior develop over a lifetime.
1 - 10 of 23

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In this section

Filter By

  • Principal Investigator / Faculty (2)
  • Research Administration (1)
  • Researcher / Lab Personnel (1)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (6)
  • Division of Hematology (4)
  • Anderson Laboratory (2)
  • Center for Applied Genomics (2)
  • Center for Autism Research (2)
  • Center for Childhood Cancer Research (2)
  • Department of Pediatrics (2)
  • Department of Radiology (2)
  • Division of Neurology (2)
  • Lifespan Brain Institute (2)
  • Bernt Laboratory (1)
  • Blobel Laboratory (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Injury Research and Prevention (1)
  • Department of Biomedical and Health Informatics (1)
  • Department of Pathology and Laboratory Medicine (1)
  • Division of Emergency Medicine (1)
  • Division of Human Genetics (1)
  • Division of Nephrology (1)
  • Division of Oncology (1)
  • Office of Academic Training and Outreach Programs (1)
  • Pediatric Center of Excellence in Nephrology (1)
  • Thomas-Tikhonenko Laboratory (1)
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