Results for Food Protein-induced Enterocolitis Syndrome

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Classic food allergies are mediated through immunoglobulin E and manifest as hives, vomiting, and anaphylaxis. Dr. Ruffner investigates the immune mechanisms of food allergy disorders which are not mediated through immunoglobulin E. In particular, the mechanisms of eosinophilic esophagitis and food-protein induced enterocolitis syndrome are of particular interest in Dr. Ruffner's laboratory.

E-mail:

ruffner [at] chop.edu

Jonathan M. Spergel, MD, PhD

Dr. Spergel focuses on translational research in IgE-mediated and non-IgE-mediated food allergy, examining novel clinical methods for desensitization and curing food allergy. His other main projects are to identify predictive factors for severity of reactions using molecular, physiologic, and clinical parameters.

E-mail:

spergel [at] chop.edu

Helping Children Outgrow Food Allergies: Q&A With Terri Brown-Whitehorn, MD

Published on

May 17, 2023

in Cornerstone Blog

Q&A With Food Allergy Researcher Terri Brown-Whitehorn, MD

Terri Brown-Whitehorn, MD, a food allergy clinical researcher for over 25 years, values being part of research families’ lives and seeing firsthand the impact of her work.

In the News: Sepsis, NIH Consortium, Allergy Study, Pincus Fellowship, STAT News

Published on

Mar 13, 2020

in Cornerstone Blog

In this roundup, read about a novel sepsis approach, a new consortium for rare genetic disorders and psychiatric conditions, and more.

Children with Food Protein-Induced Enterocolitis More Likely to Have Other Allergies

Published on

Mar 5, 2020

in Press Releases

Children with food protein-induced enterocolitis syndrome, or FPIES, have a higher chance of being diagnosed with other allergic conditions.

Food Allergy Center

Conducting laboratory, translational, and clinical research to revolutionize medications and therapies aimed at eradicating childhood food allergies.

Ruffner Laboratory

The Ruffner Lab's long-term goal is to understand how the interactions between the immune system and mucosal barrier are altered in patients with food allergies.