Results for Food Protein-induced Enterocolitis Syndrome

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Melanie A. Ruffner, MD, PhD
Melanie A. Ruffner

Classic food allergies are mediated through immunoglobulin E and manifest as hives, vomiting, and anaphylaxis. Dr. Ruffner investigates the immune mechanisms of food allergy disorders which are not mediated through immunoglobulin E. In particular, the mechanisms of eosinophilic esophagitis and food-protein induced enterocolitis syndrome are of particular interest in Dr. Ruffner's laboratory.

E-mail:
ruffner [at] chop.edu
Jonathan M. Spergel, MD, PhD
Jonathan M. Spergel Headshot

Dr. Spergel focuses on translational research in IgE-mediated and non-IgE-mediated food allergy, examining novel clinical methods for desensitization and curing food allergy. His other main projects are to identify predictive factors for severity of reactions using molecular, physiologic, and clinical parameters.

E-mail:
spergel [at] chop.edu

In the News: Sepsis, NIH Consortium, Allergy Study, Pincus Fellowship, STAT News

Published on
Mar 13, 2020
in Cornerstone Blog
In the News
In this roundup, read about a novel sepsis approach, a new consortium for rare genetic disorders and psychiatric conditions, and more.

Children with Food Protein-Induced Enterocolitis More Likely to Have Other Allergies

Published on
Mar 5, 2020
in Press Releases
Children with food protein-induced enterocolitis syndrome, or FPIES, have a higher chance of being diagnosed with other allergic conditions.

Food Allergy Center

Food Allergy Center

Conducting laboratory, translational, and clinical research to revolutionize medications and therapies aimed at eradicating childhood food allergies.

Ruffner Laboratory

Ruffner Lab

The Ruffner Lab's long-term goal is to understand how the interactions between the immune system and mucosal barrier are altered in patients with food allergies.

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