Results for Epigenetic Regulation of Gene Expression

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Craig H. Bassing, PhD
Craig H. Bassing

Dr. Bassing's research program focuses on the genetic, epigenetic, and biochemical mechanisms by which mammals develop their immune systems while suppressing autoimmunity and genomic aberrations that cause leukemia or lymphoma.

E-mail:
bassing [at] chop.edu
Kathrin M. Bernt, MD
Kathrin M. Bernt

As a physician-scientist, Dr. Bernt's goal is to further the understanding of the role of transcriptional regulation in pediatric hematopoietic stem cell biology and leukemia, and translate findings into novel therapies.

E-mail:
berntk [at] chop.edu
Kai Tan, PhD
Kai Tan

Dr. Tan studies transcriptional regulation during normal development and disease. This involves the interplay of multiple transcription and epigenetic factors in a 3D chromosomal environment. Using experimental genomics and computational modeling, Dr. Tan investigates transcriptional regulatory networks underlying embryonic hematopoiesis, T cell differentiation, and pediatric leukemia.

E-mail:
tank1 [at] chop.edu
Colin Conine, PhD
Colin C. Conine

Dr. Conine works to understand the functions of small RNAs in reproduction, epigenetic inheritance, and development. His research focuses on how small RNAs in sperm transmit epigenetic information to offspring, as well as their involvement in male fertility.

E-mail:
conine [at] chop.edu

“Encourage Diversity of Thought:” Q&A With Marco Carpenter, PhD, Diversity Fellow

Published on
Dec 20, 2021
in Cornerstone Blog
Q&A With Marco D. Carpenter, PhD, Diversity Fellow
Dr. Carpenter’s research seeks to better understand how environmental factors affect the origins of disease via epigenetic modifications.

What’s in a Sperm? Research Suggests, Stress, Diet, and Small RNAs

Published on
Aug 19, 2021
in Cornerstone Blog
Pew Scholar Studies Small RNAs in Sperm
Colin Conine, PhD, a 2021 Pew Scholar, studies small RNAs in sperm to understand how they influence traits of the offspring they produce.

LiBI Gathers Experts to Explore How Early Life Influences Neurodevelopment

Published on
Apr 12, 2019
in Cornerstone Blog
LiBI Symposium
LiBI, a unique collaborative effort, bridges the gap between pediatric and adult research to learn how brain and behavior develop over a lifetime.

2019 Distinguished Research Trainees Show Character and Creativity

Published on
Apr 11, 2019
in Cornerstone Blog
2019 Distinguished Research Trainees
Meet the four recipients of our 2019 Distinguished Research Trainee Awards at CHOP Research Institute.

Possible 'Central Hub' Proteins Found in Cancer Cell Growth

Published on
Dec 16, 2015
in Cornerstone Blog
A study from researchers at The Children’s Hospital of Philadelphia may add new lines to the textbook description of how cancer cells divide uncontrollably and develop into tumors.

Five Fascinating Facets of Beckwith-Wiedemann Syndrome

Published on
Nov 27, 2015
in Cornerstone Blog
Beckwith-Wiedemann Syndrome (BWS) is a condition that occurs when parts of the body grow too large, too fast.
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