Dr. Silverman studies the fundamental aspects of early-life commensal microbes that influence immune system development and function. He discovered that the MHC-II E molecule prevents type 1 diabetes by shaping the intestinal microbiota early in life.
Closing our Q&A series, Diversity Fellow Jean-Bernard Lubin, PhD, shares his fascination with the role of bacteria in human development and its effects on autoimmunity.
The Silverman Lab investigates early-life modifiable factors influencing the development and function of the immune system and harnesses these factors to prevent autoimmune diabetes (T1D). The lab discovered that the major histocompatibility complex class II E molecule prevents T1D by shaping the intestinal microbiota early in life.
