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Results for Clotting Factors

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1 - 10 of 31

Benjamin J. Samelson-Jones, MD, PhD
Benjamin J. Samelson-Jones

Dr. Samelson-Jones is a pediatric hematologist dedicated to improving the lives of children with bleeding and clotting disorders. His research focuses on gene therapy for hemophilia, the biochemical basis of coagulation, and the immune responses to hemophilia therapies.

E-mail:
samelsonjonesb [at] chop.edu
Rodney M. Camire, PhD
Rodney M. Camire Headshot

Dr. Camire's research focuses on understanding the components of the blood coagulation system, how they interface with activated cells, and how disturbances in their function lead to bleeding and thrombosis. He is also interested in developing novel therapeutic approaches (protein, gene-based, small molecule) to mitigate these events, which are major causes of morbidity and mortality worldwide.

E-mail:
camire [at] chop.edu
Lindsey A. George, MD
Lindsey A. George

Dr. George's basic and clinical research interests are in the development of novel therapeutics for hemophilia. Her basic science laboratory studies the molecular basis of coagulation, and she is the principal investigator of ongoing hemophilia A and B gene therapy trials.

E-mail:
georgel [at] chop.edu

In The News: MIS-C, Antibody Treatment for Eosinophilic Esophagitis, ASH 2022

Published on
Jan 6, 2023
in Cornerstone Blog
Our Scientists’ Research Highlighted In the News
See highlights of work by Children’s Hospital of Philadelphia researchers that is leading to novel findings.

Research Shows Multiyear Factor VIII Expression After Hemophilia A Gene Therapy

Published on
Nov 19, 2021
in Cornerstone Blog
A one-time treatment with an adeno-associated viral vector demonstrated safe, sustained factor VIII expression for patients with hemophilia A.
Dr. Lindsey George and colleagues report safe and sustained expression following hemophilia A gene therapy.

CHOP-led Study Shows Novel Gene Therapy for Hemophilia A Leads to Sustained Expression of Clotting Factor and Reduced Bleeding Events

Published on
Nov 17, 2021
in Press Releases
Results from multicenter study are first to show improved production of coagulation factor VIII over prolong period, reducing bleeding events.

In The News: COVID-19 Depression, Outstanding Science Award, Sports Injuries, Junior Investigator Awards, Philadelphia Magazine

Published on
May 14, 2021
in Cornerstone Blog
In the News
This week’s research news features Ran Barzilay, PhD, and the results of the latest COVID-19 Resilience Project from the Lifespan Brain Institute.

Researchers Uncover a Previously Underappreciated Mechanism that Turns Off Clotting Factor in Hemophilia A

Published on
Jan 13, 2021
in Press Releases
CHOP researchers identified an in vivo role for activated protein C (APC), which could be a target for hemophilia A treatments.

Dr. Krishnaswamy Recognized for Groundbreaking Research of Blood Clots

Published on
Dec 18, 2019
in Cornerstone Blog
Sriram Krishnaswamy, PhD
Sriram Krishnaswamy, PhD, receives ASH’s 2019 prestigious Ernest Beutler Lecture award and gives talk at Society’s annual meeting in Florida.

In the News: Chromatin Rebuilding, Hemophilia Oral Treatment, Linking CVD and CKD, New Algorithm Detects Genetic Variants

Published on
Dec 13, 2019
in Cornerstone Blog
In the News
Learn about developments in chromatin rebuilding, novel hemophilia treatment, linking heart and kidney disease, and genetic sequencing.
1 - 10 of 31

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In this section

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  • Division of Hematology (14)
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  • Pediatric Center of Excellence in Nephrology (1)
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  • Research Vector Core (1)
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In this section

Filter By

  • Principal Investigator / Faculty (3)

Organizations

  • Division of Hematology (14)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (8)
  • Department of Pediatrics (4)
  • Center for Applied Genomics (3)
  • Department of Anesthesiology and Critical Care Medicine (3)
  • Division of Endocrinology and Diabetes (3)
  • Division of Oncology (3)
  • PolicyLab (3)
  • Center for Autism Research (2)
  • Center for Injury Research and Prevention (2)
  • Clinical Futures (2)
  • Department of Biomedical and Health Informatics (2)
  • Division of Nephrology (2)
  • PennCHOP Microbiome Program (2)
  • Center for Childhood Cancer Research (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Mitochondrial and Epigenomic Medicine (1)
  • Center for Violence Prevention (1)
  • Clinical In Vivo Gene Therapy (1)
  • Comprehensive Bone Marrow Failure Center (1)
  • Department of Radiology (1)
  • Division of Allergy and Immunology (1)
  • Division of Cardiology (1)
  • Division of Gastroenterology, Hepatology, and Nutrition (1)
  • Division of Human Genetics (1)
  • Division of Neurology (1)
  • Division of Neurosurgery (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Leukodystrophy Center of Excellence (1)
  • Lifespan Brain Institute (1)
  • Margaritis Laboratory (1)
  • Novel Therapeutics for Bleeding Disorders (1)
  • Pediatric Center of Excellence in Nephrology (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Research in the Department of Child and Adolescent Psychiatry and Behavioral Services (1)
  • Research Vector Core (1)
  • Stress Neurobiology Program (1)
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