John M. Maris, MD, is leading a pediatric immuno-oncology Center for Discovery and Development of Optimal Immunotherapeutic Strategies for Childhood Cancers with support from the NCI Moonshot Initiative.
Vice President Joe Biden’s ambitious “Moonshot” initiative is aimed at boosting and streamlining cancer research across the country. We asked Andrei Thomas-Tikhonenko, PhD, chief of the Division of Cancer Pathobiology and an investigator for the Center for Childhood Cancer Research at The Children’s Hospital of Philadelphia, to share his thoughts on how this strategic plan is changing the landscape of pediatric cancer research.
The Computational Epigenetics Lab develops novel algorithms and big data analytics to understand epigenetic cell identity and its dynamics in cell fate transition, organismal development, and human disease. The team disentangles cellular and physiological processes that impact DNA methylation and chromatin states.