Results for Bacterial Pathogenesis

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Joseph W. St. Geme, III, MD
Joseph W. St. Geme

Dr. St. Geme's research focuses on bacterial pathogenesis, with an emphasis on defining the molecular and cellular determinants of Haemophilus influenzae and Kingella kingae disease.

E-mail:
stgemeIIIj [at] chop.edu
Joseph P. Zackular, PhD
Joseph P. Zackular

Dr. Zackular's research is focused on understanding how interactions between the host, gut microbiota, and pathogenic microbes impact human health and disease. His recent efforts center on understanding how the important nosocomial pathogen, Clostridium difficile, interacts with resident gut microbiota during infection and how interspecies cross-talk impacts growth, behavior, and virulence of this pathogen.

E-mail:
zackularj [at] chop.edu

CHOP Research Poster Day and Scientific Symposium: Making the Microbiome Less Mysterious

Published on
May 15, 2023
in Cornerstone Blog
Making the Microbiome Less Mysterious
This year’s Poster Day and Scientific Symposium featured all manners of bugs, breakthroughs, and big discoveries.

Snapshot Science: Is a Vaccine Against Nontypeable Haemophilus Influenzae on the Horizon?

Published on
Aug 3, 2021
in Cornerstone Blog
Potential Vaccine Against Nontypeable Haemophilus Influenza
CHOP researchers identify potential vaccine approach against nontypeable Haemophilus Influenzae (NTHi) — the most common cause of bacterial respiratory tract infection.

Physician-in-Chief Cultivates Sense of Wonder Inspired by His Dad

Published on
Jun 21, 2020
in Cornerstone Blog
Dr. St. Geme with his father
Dr. St. Geme builds upon his father’s legacy to advance child health with his own research contributions and a focus on holistic care.

In the Gut: Therapeutic Discovery in the Microbiome

Published on
Nov 21, 2018
in Cornerstone Blog
microbiome
Scientists from the PennCHOP Microbiome Program shared new developments in knowledge of the microbiome at their Fifth Annual Symposium.

Why Can Commensal Organisms Cause Infections?

Published on
Mar 12, 2014
in Cornerstone Blog
Despite its somewhat misleading name, H. influenzae does not cause influenza, but is instead associated with invasive infections and localized respiratory tract disease.

St. Geme Laboratory

St. Geme Lab

The St. Geme Lab focuses on bacterial pathogenesis, with an emphasis on defining the molecular and cellular determinants of Haemophilus influenzae and Kingella kingae disease.

Division of Infectious Diseases

Division of Infectious Diseases

Using state-of-the-art data sources, techniques and tools, the research programs within the Division of Infectious Diseases seek to define the mechanisms and outcomes of a wide array of infectious microbes and disease processes.

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