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Results for B Cell Tolerance

1 - 10 of 33

Neil D. Romberg, MD
Neil D. Romberg

Dr. Romberg investigates the regulatory mechanisms enabling our immune systems to fight infections without injuring ourselves. He is particularly interested in the immune system of patients with primary immunodeficiency who are susceptible to both life-threatening infections and autoimmune diseases. Greater insights into these rare diseases may enable rationale development of targeted therapies for more common diseases with an immunologic basis.

E-mail:
rombergn [at] chop.edu
Benjamin J. Samelson-Jones, MD, PhD
Benjamin J. Samelson-Jones

Dr. Samelson-Jones is a pediatric hematologist dedicated to improving the lives of children with bleeding and clotting disorders. His research focuses on gene therapy for hemophilia, the biochemical basis of coagulation, and the immune responses to hemophilia therapies.

E-mail:
samelsonjonesb [at] chop.edu
Andrew D. Wells, PhD
Andrew D. Wells

Dr. Wells studies the genetic, epigenetic, and transcriptional mechanisms that control T lymphocyte immunity and tolerance.

E-mail:
wellsa [at] chop.edu
Leyuan Ma, PhD
Leyuan Ma

Dr. Ma focuses on immune engineering. He leverages genetic, chemistry, and engineering tools to dissect immune cell-cell and cell-tissue crosstalk and harness these crosstalk mechanisms to develop biomaterials, protein, and cell-based precision immunotherapies for cancer and autoimmune diseases.

E-mail:
mal5 [at] chop.edu

CHOP Research Institute Scientific Symposium: Harnessing the Immune Response

Published on
Jun 2, 2022
in Cornerstone Blog
Scientific Symposium 2022: Harnessing the Immune Response
CHOP and Penn researchers discussed the latest findings about the mechanisms of immunity at the CHOP Research Institute 2022 Scientific Symposium.

Snapshot Science: Can Exendin-(9-39) Treat Congenital HI in Children?

Published on
Apr 13, 2022
in Cornerstone Blog
Can Exendin-(9-39) Treat Congenital HI in Children?
New evidence from CHOP researchers supports the use of exendin-(9-39) as an effective treatment for children with HI.

In the News: Type 1 Diabetes, CZI Grant, Cystic Fibrosis, Mitochondrial Disease

Published on
Sep 3, 2021
in Cornerstone Blog
In the News: Diabetes, CZI Grant, Cystic Fibrosis, Mitochondrial Disease
This week’s In the News highlights two new studies, a new grant, the new director of the Cystic Fibrosis Center, and a physician’s new role.

Exploring Exosome-Mediated Stem Cell Engraftment for Hemoglobinopathies

Published on
May 8, 2019
in Cornerstone Blog
Meghana V. Kashyap, MD
A surgeon-scientist explores exosome-mediated stem cell engraftment as a means to lessen disease severity and enhance quality of life for children with hemoglobinopathies.

Pioneering Novel Therapies for Hemophilia

Published on
Sep 20, 2018
in Cornerstone Blog
hemophilia
Two exciting lines of research build on what we know about hemophilia to improve existing treatments.

In the News: ROP Screening Tool, Sickle Cell Disease Target, PolicyLab Keynote, 2018 St. Baldrick's Grants

Published on
Jul 27, 2018
in Cornerstone Blog
CHOP Research In the News
Don't miss new findings from our ophthalmology and hematology researchers into retinopathy of prematurity and sickle cell disease.
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In this section

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  • Principal Investigator / Faculty (4)

Organizations

  • Division of Endocrinology and Diabetes (7)
  • Department of Pathology and Laboratory Medicine (4)
  • Advancement of Hyperinsulinism Care and Research (3)
  • Congenital Hyperinsulinism Research Laboratory (3)
  • De León-Crutchlow Laboratory (3)
  • Department of Pediatrics (2)
  • Division of Pulmonary and Sleep Medicine (2)
  • Mitochondrial Medicine (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Ackermann Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Applied Genomics (1)
  • Clinical In Vivo Gene Therapy (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Division of Allergy and Immunology (1)
  • Division of Cancer Pathobiology (1)
  • Division of Hematology (1)
  • Division of Infectious Diseases (1)
  • Division of Neurology (1)
  • Division of Oncology (1)
  • Division of Protective Immunity (1)
  • Division of Rheumatology (1)
  • Grant Laboratory (1)
  • PolicyLab (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Wells Laboratory (1)

In this section

Filter By

  • Principal Investigator / Faculty (4)

Organizations

  • Division of Endocrinology and Diabetes (7)
  • Department of Pathology and Laboratory Medicine (4)
  • Advancement of Hyperinsulinism Care and Research (3)
  • Congenital Hyperinsulinism Research Laboratory (3)
  • De León-Crutchlow Laboratory (3)
  • Department of Pediatrics (2)
  • Division of Pulmonary and Sleep Medicine (2)
  • Mitochondrial Medicine (2)
  • Spatial and Functional Genomics Research Affinity Group (2)
  • Ackermann Laboratory (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Applied Genomics (1)
  • Clinical In Vivo Gene Therapy (1)
  • Cystic Fibrosis-Related Diabetes Research Program (1)
  • Division of Allergy and Immunology (1)
  • Division of Cancer Pathobiology (1)
  • Division of Hematology (1)
  • Division of Infectious Diseases (1)
  • Division of Neurology (1)
  • Division of Oncology (1)
  • Division of Protective Immunity (1)
  • Division of Rheumatology (1)
  • Grant Laboratory (1)
  • PolicyLab (1)
  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (1)
  • Romberg Laboratory (1)
  • Spatial and Functional Genomics Collaborative (1)
  • Wells Laboratory (1)
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