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Results for Animal Models

1 - 10 of 196

Geary "Chip" Smith, DVM, MS
Geary "Chip" Smith

Dr. Smith is a laboratory animal medicine veterinarian. As Technical Director of the CCMT Comparative Medicine Services Core, he helps guide promising therapeutics and devices from discovery and developmental studies through nonclinical studies.

E-mail:
smithgr [at] chop.edu
Patrick J. Cahill, MD
Patrick J. Cahill

Dr. Cahill's focuses on improving treatments for patients with early onset chest and spinal deformity, employing a combination of clinical, biomechanical, and basic science research approaches.

E-mail:
cahillp1 [at] chop.edu
Seema Bhatnagar, PhD
Seema Bhatnagar

Dr. Bhatnagar's research aims to further the understanding of the neural basis of individual differences in response to stressful experiences. This includes identifying neural substrates that produce resiliency or vulnerability to the effects of stress and determining treatments to mitigate vulnerability and to promote resiliency through both preclinical and translational studies.

E-mail:
bhatnagars [at] chop.edu
Louis R. Ghanem, MD, PhD
Louis R. Ghanem, MD, PhD

Dr. Ghanem investigates the impact of transcriptional gene expression controls and mRNA processing upon the severity and progression of pediatric inflammatory bowel disease.

E-mail:
ghaneml [at] chop.edu
David R. Lynch, MD, PhD
David R. Lynch

Dr. Lynch maintains a dynamic program that involves clinical, translational, and basic science research efforts focused on the rare disease Friedreich ataxia.

E-mail:
lynch [at] chop.edu
Evelyn K. Shih, MD, PhD
Evelyn K. Shih, MD, PhDEvelyn K. Shih, MD, PhD

Dr. Shih studies the metabolic interplay between cell types within the neurovascular unit during stroke to develop effective, novel mitochondrial-directed therapeutics to improve post-stroke disability. She works with small and large animal models of childhood arterial ischemic stroke.

E-mail:
shihe [at] chop.edu
Alan W. Flake, MD
Alan W. Flake

Dr. Flake is a general pediatric surgeon with a clinical and research focus on prenatal treatment ranging from the fetal surgical repair of anatomic anomalies to prenatal stem cell and gene therapy. He has extensive experience in developing rodent, canine, and sheep models for in utero transplantation and for investigating fetal surgery for anatomic malformations.

E-mail:
flake [at] chop.edu
Valder R. Arruda, MD, PhD
Valder R. Arruda

The development of gene-based strategies for the treatment of bleeding and thrombotic diseases is at the heart of research by Dr. Arruda. Working collaboratively, Dr. Arruda and his colleagues have carried out early-phase clinical studies on adeno-associated viral vectors for the treatment of severe hemophilia B.

E-mail:
arruda [at] chop.edu
Paris Margaritis, DPhil
Paris Margaritis

Dr. Margaritis uses biochemical, molecular, and complex in vivo methodology within the field of coagulation to advance the understanding of molecular mechanisms involved in pro- and anti-coagulant reactions, and translate research for the treatment of coagulation defects.

E-mail:
margaritis [at] chop.edu
Beverly L. Davidson, PhD
Photo of Beverly L. Davidson, PhD

Dr. Davidson works to understand the molecular basis of childhood onset neurodegenerative diseases and the development of gene and small molecule therapies for treatment. She also focuses on how noncoding RNAs participate in neural development and neurodegenerative disease processes, and how they can be harnessed for therapies.

E-mail:
davidsonbl [at] chop.edu
1 - 10 of 196

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In this section

Filter By

  • Principal Investigator / Faculty (25)
  • Researcher / Lab Personnel (3)
  • Research Administration (1)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (19)
  • Department of Pediatrics (16)
  • Center for Mitochondrial and Epigenomic Medicine (10)
  • Center for Injury Research and Prevention (9)
  • Division of Hematology (8)
  • Center for Applied Genomics (7)
  • Department of Anesthesiology and Critical Care Medicine (7)
  • Division of Oncology (7)
  • PolicyLab (7)
  • Center for Autism Research (6)
  • Center for Childhood Cancer Research (6)
  • Department of Biomedical and Health Informatics (6)
  • Department of Child and Adolescent Psychiatry (6)
  • Division of Infectious Diseases (6)
  • Division of Neurology (6)
  • Mitochondrial Medicine (6)
  • Department of Radiology (5)
  • Department of Surgery (5)
  • Division of Endocrinology and Diabetes (5)
  • Division of Human Genetics (5)
  • Division of Neonatology (5)
  • Lifespan Brain Institute (5)
  • Department of Pathology and Laboratory Medicine (4)
  • Division of Gastroenterology, Hepatology, and Nutrition (4)
  • Jill and Mark Fishman Center for Lymphatic Disorders (4)
  • Division of Allergy and Immunology (3)
  • Ahrens-Nicklas Laboratory (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Pediatric Airway Disorders (2)
  • Center for Pediatric Clinical Effectiveness (2)
  • Center for the Investigation of Factor FVIII Immunogenicity (2)
  • Children’s Oncology Group (2)
  • Division of Cardiology (2)
  • Division of Orthopaedic Surgery (2)
  • Division of Urology (2)
  • Inflammatory Bowel Disease Center (2)
  • Intellectual and Developmental Disabilities Research Center (2)
  • Lurie Family Foundations MEG Imaging Center (2)
  • Office of Academic Training and Outreach Programs (2)
  • PennCHOP Microbiome Program (2)
  • Rivella Laboratory (2)
  • St. Geme Laboratory (2)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (2)
  • Aquatic Zebrafish Core (1)
  • Bailis Laboratory (1)
  • Beckwith-Wiedemann Syndrome Program of Excellence (1)
  • Bhoj Laboratory (1)
  • Biomedical Optical Devices to Monitor Cerebral Health (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Pediatric Heart Valve Disorders (1)
  • CHOP Postdoctoral Alliance (1)
  • Davidson Laboratory (1)
  • Developmental Biology Research Affinity Group (1)
  • Division of Emergency Medicine (1)
  • Division of General Pediatrics (1)
  • Division of Ophthalmology (1)
  • Division of Protective Immunity (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Feudtner Laboratory (1)
  • Food Allergy Center (1)
  • Fred and Suzanne Biesecker Pediatric Liver Center (1)
  • Hamilton Laboratory (1)
  • John Laboratory (1)
  • Kilbaugh Laboratory (1)
  • Leukodystrophy Center of Excellence (1)
  • Margaritis Laboratory (1)
  • Maris Laboratory (1)
  • Mir Laboratory (1)
  • Mitchell Laboratory (1)
  • Mitochondria Research Affinity Group (1)
  • Neuroscience Research Affinity Group (1)
  • Optical Neuroimaging Laboratory (1)
  • Pacifici Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Roberts Individualized Medical Genetics Center (1)
  • Silverman Laboratory (1)
  • Stress Neurobiology Program (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
  • Wallace Laboratory (1)
  • Wolfe Lab (1)

In this section

Filter By

  • Principal Investigator / Faculty (25)
  • Researcher / Lab Personnel (3)
  • Research Administration (1)

Organizations

  • Raymond G. Perelman Center for Cellular and Molecular Therapeutics (19)
  • Department of Pediatrics (16)
  • Center for Mitochondrial and Epigenomic Medicine (10)
  • Center for Injury Research and Prevention (9)
  • Division of Hematology (8)
  • Center for Applied Genomics (7)
  • Department of Anesthesiology and Critical Care Medicine (7)
  • Division of Oncology (7)
  • PolicyLab (7)
  • Center for Autism Research (6)
  • Center for Childhood Cancer Research (6)
  • Department of Biomedical and Health Informatics (6)
  • Department of Child and Adolescent Psychiatry (6)
  • Division of Infectious Diseases (6)
  • Division of Neurology (6)
  • Mitochondrial Medicine (6)
  • Department of Radiology (5)
  • Department of Surgery (5)
  • Division of Endocrinology and Diabetes (5)
  • Division of Human Genetics (5)
  • Division of Neonatology (5)
  • Lifespan Brain Institute (5)
  • Department of Pathology and Laboratory Medicine (4)
  • Division of Gastroenterology, Hepatology, and Nutrition (4)
  • Jill and Mark Fishman Center for Lymphatic Disorders (4)
  • Division of Allergy and Immunology (3)
  • Ahrens-Nicklas Laboratory (2)
  • Center for Data-Driven Discovery in Biomedicine (2)
  • Center for Pediatric Airway Disorders (2)
  • Center for Pediatric Clinical Effectiveness (2)
  • Center for the Investigation of Factor FVIII Immunogenicity (2)
  • Children’s Oncology Group (2)
  • Division of Cardiology (2)
  • Division of Orthopaedic Surgery (2)
  • Division of Urology (2)
  • Inflammatory Bowel Disease Center (2)
  • Intellectual and Developmental Disabilities Research Center (2)
  • Lurie Family Foundations MEG Imaging Center (2)
  • Office of Academic Training and Outreach Programs (2)
  • PennCHOP Microbiome Program (2)
  • Rivella Laboratory (2)
  • St. Geme Laboratory (2)
  • Wolfson Family Laboratory for Clinical and Biomedical Optics (2)
  • Aquatic Zebrafish Core (1)
  • Bailis Laboratory (1)
  • Beckwith-Wiedemann Syndrome Program of Excellence (1)
  • Bhoj Laboratory (1)
  • Biomedical Optical Devices to Monitor Cerebral Health (1)
  • Cancer Immunotherapy (CAR-T) (1)
  • Cell and Gene Therapy Collaborative (1)
  • Center for Child Injury Prevention Studies (1)
  • Center for Computational and Genomic Medicine (1)
  • Center for Pediatric Heart Valve Disorders (1)
  • CHOP Postdoctoral Alliance (1)
  • Davidson Laboratory (1)
  • Developmental Biology Research Affinity Group (1)
  • Division of Emergency Medicine (1)
  • Division of General Pediatrics (1)
  • Division of Ophthalmology (1)
  • Division of Protective Immunity (1)
  • Division of Pulmonary and Sleep Medicine (1)
  • Fetal Biology and Therapy Research Affinity Group (1)
  • Feudtner Laboratory (1)
  • Food Allergy Center (1)
  • Fred and Suzanne Biesecker Pediatric Liver Center (1)
  • Hamilton Laboratory (1)
  • John Laboratory (1)
  • Kilbaugh Laboratory (1)
  • Leukodystrophy Center of Excellence (1)
  • Margaritis Laboratory (1)
  • Maris Laboratory (1)
  • Mir Laboratory (1)
  • Mitchell Laboratory (1)
  • Mitochondria Research Affinity Group (1)
  • Neuroscience Research Affinity Group (1)
  • Optical Neuroimaging Laboratory (1)
  • Pacifici Laboratory (1)
  • Pennsylvania Pediatric Medical Device Consortium (1)
  • Roberts Individualized Medical Genetics Center (1)
  • Silverman Laboratory (1)
  • Stress Neurobiology Program (1)
  • Translational Research Program in Pediatric Orthopaedics (1)
  • Wallace Laboratory (1)
  • Wolfe Lab (1)
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