Results for Alpha Cell

1 - 10 of 28

Dr. Ackermann studies diabetes (types 1 and 2) and congenital hyperinsulinism using mouse models, cell lines, and primary human tissue. She aims to identify novel pathways regulating beta cell insulin secretion, leading to innovative therapeutic strategies for these disorders. Current studies include in vivo mouse physiology, ex vivo human islet physiology, CRISPR-Cas9 gene editing, epigenetic modification, and single-cell functional genomics.

E-mail:

ackermanna [at] chop.edu

Alexis Thompson

Dr. Thompson is the chief of the Division of Hematology at CHOP and holds the Elias Schwartz, MD, Endowed Chair in Hematology. Her research focuses on sickle cell disease and thalassemia.

E-mail:

thompsona7 [at] chop.edu

Stanley Stachelek, PhD

Dr. Stachelek's research interests are in the cellular and molecular mechanisms that control vasculature inflammation.

E-mail:

stachelek [at] chop.edu

Sarah A. Richman, MD, PhD

Dr. Richman's research focuses on chimeric antigen receptor (CAR) T cells targeting solid tumors with the goal of translating these findings to this unmet clinical need.

E-mail:

richmans [at] chop.edu

Jennifer Pogoriler, MD, PhD

Dr. Pogoriler's research focuses on pediatric lung disease and neoplasia. These interests come together in her work on congenital cystic lung lesions and their potential premalignant diagnosis. She collaborates with both clinicians and basic scientists on pediatric cancer research.

E-mail:

pogorilerj [at] chop.edu

Rachana Shah, MD, MSTR

Dr. Shah's research is centered on understanding obesity and its related complications. Her current work includes clinical and translational studies exploring pathophysiology and modulation of obesity-related adipose tissue and systemic inflammation using human cell lines and clinical trials. She is also involved in clinical studies of outcomes and risk factors of polycystic ovarian syndrome and type 2 diabetes in teens.

E-mail:

shahr [at] chop.edu

Robert O. Heuckeroth, MD, PhD

Dr. Heuckeroth investigates mechanisms controlling bowel motility in order to find new ways to treat, diagnose, and prevent intestinal motility disorders. His research is focused on enteric nervous system and smooth muscle biology as he works to find new ways to improve the lives of children with bowel motility disorders.

E-mail:

heuckerothr [at] chop.edu

Eugene Khandros, MD, PhD

Dr. Eugene Khandros is a physician-scientist with a clinical and research focus on disorders of red blood cells and hemoglobin production.

E-mail:

khandrose [at] chop.edu

John M. Maris, MD

Dr. Maris investigates the molecular and genetic mechanisms contributing to the development and progression of neuroblastoma, a common childhood cancer. He also aims to develop new molecular diagnostic tests and less toxic, targeted therapies to treat relapsed or refractory neuroblastoma, including a major effort in immunotherapy discovery and development.

E-mail:

maris [at] chop.edu

Ryan W. Morgan, MD, MTR

Dr. Morgan is a resuscitation scientist who studies pediatric cardiac arrest and cardiopulmonary resuscitation (CPR) through both translational laboratory work and clinical studies. His focus is to identify disease-specific pathophysiology that can be specifically targeted during CPR.

E-mail:

morganr1 [at] chop.edu