Radiology Clinical Research Core Funded Research

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Investigators in the Department of Radiology's Clinical Research Core are supported in their pursuit of innovation and excellence in diagnostic imaging research with grants from a variety of sources.

Quantitative Image Modeling for Brain Tumor Analysis and Tracking (Old Dominion)
Sponsor: National Institutes of Health (NIH)
PI: Arastoo Vossough

Noninvasive Portal Pressure Measurements in Children
Sponsor: National Institutes of Health
PI: Sudha Anupindi

Ultrasound Quantification for Pediatric Kidney UTD
Sponsor: Philips Ultrasound
PI: Susan Back

Junior Pilot Program Targeted Delivery of Xenon Encapsulated Liposomes for Neonatal Neuroprotection
Sponsor: Children's Hospital of Philadelphia
PI: Misun Hwang

Philips Works-in-Progress (WIPs)
Sponsor: Philips Electronics North America Corporation
PI: Susan Back

Contrast-Enhanced Brain Ultrasound on Extreme Premature Fetal Lambs Maintained by the EXTra-uterine Environment for Neonatal Support (EXTEND): Visibility Study and Evaluation of Perfusion Parameters Drug only
Sponsor: Lantheus Holdings, Inc
PI: Ryne Didier

Contrast-Enhanced Brain Ultrasound in Extreme Premature Fetal Lambs Maintained by the EXTra-uterine Environment for Neonatal Support (EXTEND): Evaluation of Perfusion Parameters and Assessment of Intracranial Pressure
Sponsor: The Society for Pediatric Radiology
PI: Ryne Didier

GE Ultrasound- Works –in – Progress (WIPs) Study
Sponsor: General Electric Co
PI: Anush Sridharan

Osteosarcoma: Improving Operative Planning Through MR Bone Imaging and 3D Osteochondral Modeling
Sponsor: Radiological Society of North America
PI: Jie Nguyen

Defining bone sarcoma tumor margin using novel MRI biomarkers
Sponsor: Children's Cancer Research Fund
PI: Jie Nguyen

Voyager/Mustang 4.0 AIUS ultrasound system Marketing Clinical Study
Sponsor: Philips Ultrasound
PI: Beverly Coleman

Contrast Enhancement Characteristics of Gadolinium-Based-Contrast-Agents (GBCA) in Functional MR Urography (fMRU)
Sponsor: Guerbet Consulting LLC
PI: Hansel Otero

Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal Hydrocephalus
Sponsor: National Institutes of Health (NIH)
PI: Misun Hwang

Evaluation of bowel perfusion with contrast-enhanced ultrasound in necrotizing enterocolitis
Sponsor: Bracco Diagnostics, Inc
PI: Misun Hwang

Generalized Protocol for Studying New Ultrasound (US) Techniques (Works-in-progress - US WIPs)
Sponsor: National Institutes of Health (NIH)
PI: Anush Sridharan

CEUS Evaluation of Intracranial Pressure in Hydrocephalus
Sponsor: Radiological Society of North America
PI: Misun Hwang

Improved diagnosis and prognostication of hypoxic ischemic injury in neonates and infants using Contrast-Enhanced Ultrasound
Sponsor: Bracco Diagnostics, Inc
PI: Misun Hwang

Clarity Transparent Face Mask
Sponsor: Children's Research Institute (Children’s National Medical Center)
PI: Maria Velez

Neuroprotection with Xenon Microbubbles post Cardiac Arrest
Sponsor: University of Pennsylvania
PI: Misun Hwang

Acute Flaccid Myelitis (IPA)
Sponsor: Centers for Disease Control and Prevention (CDC)
PI: Arastoo Vossough

Treating Brain Swelling in Pediatric Cerebral Malaria
Sponsor: National Institutes of Health (NIH)
PI: Lorenna Vidal

Stress ultrasonography and elastography of the ulnar collateral ligament
Sponsor: Society for Pediatric Radiology
PI: Liya Gendler

Percutaneous Ultrasound Gastrostomy: Clinical Evaluation of a Pediatric Method for Feeding Tube Placement
Sponsor: National Institutes of Health (NIH)
PI: Anne-Marie Cahill

Presumed Low-Grade Gliomas in the Pediatric Population: Imaging Features as Predictors of Outcomes
Sponsor: American Society of Neuroradiology
PI: Susan Sotardi

Renal MRI Biomarkers: The Route to Clinical Adoption
Sponsor: National Institutes of Health (NIH)
PI: Suraj Serai

Implementing Precision Education in Radiology Via an Adaptive Learning "Tutor"
Sponsor: The Society for Pediatric Radiology
PI: Janet Reid

Bracco Consulting and Services Agreement Lumason Training Services Agreement
Sponsor: Bracco Diagnostics, Inc
PI: Kassa Darge

Intelligent Tutor: Push Technology Integrated Within a Learning Management System (LMS)
Sponsor: University of Pennsylvania
PI: Ami Gokli

Integrative Imaging Biomarker Assessment of Hepatic Involvement and Severity in Gaucher Disease to Tailor Personalized Therapy
Sponsor: The Society for Pediatric Radiology
PI: Andrew Degnan

Novel Ultrasound Markers of Brain Injury in Neonatal Extracorporeal Membrane Oxygenation Following Ischemia-Reperfusion Injury
Sponsor: Children's Hospital of Philadelphia
PI: Misun Hwang

Improved Diagnosis and Prognostication of Neonatal Hypoxic Ischemic Injury With Combined Contrast Enhanced Ultrasound and Elastography
Sponsor: Radiological Society of North America
PI: Misun Hwang

NIH/CTSI KL2 Award
Sponsor: National Institutes of Health (NIH)
PI: Misun Hwang

3D/3D Fusion and iGuide Software for Navigation and Targeting in Interventional Radiology
Sponsor: Siemens Med Solutions USA, Inc
PI: Anne Marie Cahill

ASPNR Vossough Award
Sponsor: American Society of Pediatric Neuroradiology
PI: Arastoo Vossough

Contrast-Enhanced Brain Ultrasound on Extreme Premature Fetal Lambs Maintained by the EXTrauterine Environment for Neonatal Support (EXTEND)
Sponsor: University of Pennsylvania
PI: Ryne Didier

Contrast-Enhanced Ultrasound in Brain Perfusion
Sponsor: Radiological Society of North America
PI: Ryne Didier

Advanced imaging, guidance and analysis for pediatric interventional radiology
Sponsor: Siemens Med Solutions USA, Inc
PI: Anne Marie Cahill

Penn CHOP Radiotracer, Radioactive Tracer Agreement
Sponsor: University of Pennsylvania
PI: Kassa Darge

Cincinnati Children's Hospital Medical Center Sub Contract: Determination of Normal Liver Stiffness by MR Elastography in Children
Sponsor: The Society for Pediatric Radiology
PI: Kassa Darge

LPHR Collimator assessment
Sponsor: Siemens Med Solutions USA, Inc
PI: Lisa States

Detection of Brain Perfusion Abnormalities in a Porcine Model of ECMO with Contrast-Enhanced Ultrasound
Sponsor: Radiological Society of North America
PI: Misun Hwang

Federated Machine Learning to Automate Early Cancer Detection
Sponsor: Mark Foundation for Cancer Research
PI: Lisa States