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William H. Peranteau, MD
Attending Surgeon
Dr. Peranteau is an attending surgeon in the Division of Pediatric General, Thoracic and Fetal Surgery and an associate professor of Surgery at CHOP. His research interest is in fetal development as it relates to the potential understanding of and fetal intervention for congenital anomalies.
Bio
Dr. Peranteau's areas of interest include fetal biology, fetal and neonatal surgery, and general pediatric surgery. A native of Gloucester City, New Jersey, he earned his bachelor’s degree in molecular biology from Princeton University, and his medical degree from the University of Pennsylvania. Dr. Peranteau joined the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment team in 2012.
Prior to joining the center, Dr. Peranteau held a fellowship in pediatric general surgery at CHOP. He also served as a research fellow with CHOP’s Center for Fetal Research, where he investigated the role of in utero bone marrow and stem cell transplantation for the management of congenital hematologic disorders such as sickle cell disease.
“This area of research is potentially readily translatable to clinical application,” Dr. Peranteau said. “The group of people not only within the Department of Pediatric General Surgery and the Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment but also the CHOP community as a whole, with experts in every field of pediatrics, make CHOP an unbelievable place to work and a place that’s ripe for advancing clinical medicine.”
Dr. Peranteau has published articles in the Journal of the American College of Surgeons, the Journal of Pediatric Surgery, Fetal Diagnosis and Therapy, Experimental Hematology, and Blood. He is board certified in pediatric surgery and general surgery.
Education and Training
MD, University of Pennsylvania School of Medicine
General Surgery Internship, Brigham and Women's Hospital, Boston, MA
Research Fellowship, Children's Hospital of Philadelphia
Pediatric Surgery Fellowshiip, Children's Hospital of Philadelphia
Titles and Academic Titles
Attending Surgeon
Associate Professor of Surgery
Adzick-McCausland Distinguished Chair in Fetal and Pediatric Surgery
Professional Memberships
American College of Surgeons, 2008-
American Pediatric Surgical Association, 2014-
American Pediatric Surgical Association, 2015-
International Fetal Transplantation and Immunology Society, 2015-
Treasurer, 2017-
American Society of Gene and Cell Therapy, 2017-
Association for Academic Surgery, 2018-
Professional Awards
NIH Director’s New Innovator Award, NIH Common Fund’s High Risk, High Reward Program, 2019-2024
Institute for Translational Medicine and Therapeutics Collaborative Research Award, University of Penn, 2019-2020
Institute for Translational Medicine and Therapeutics Collaborative Research Award, University of Penn, 2017-2018
The Orphan Disease Center Genome Editing for the Treatment of Rare Diseases Pilot Grant Award, 2016-2017
American Pediatric Surgical Association Foundation Award, 2015-2016
Protective Immunity and Immunopathology Affinity Group Pilot Grant Award, Children’s Hospital of Philadelphia, 2015-2016
The Gerber Foundation Novice Research Award, 2013-2016
The Gerber Foundation Novice Research Award, 2013-2015
Robert T. Osteen Teaching Award, Brigham & Women's Hospital/Harvard Medical School, 2010
Surgery Resident Teaching Award, Tufts University School of Medicine, 2008, 2010
Publication Highlights
O'Connell AE, Guseh S, Lapteva L, Cummings CL, Wilkins-Haug L, Chan J, Peranteau WH, Almeida-Porada G, Kourembanas S. Gene and Stem Cell Therapies for Fetal Care: A Review. JAMA Pediatr. 2020 Oct; 174(10): 985-991. PubMed PMID: 32597943
Oliver ER, DeBari SE, Didier RA, Johnson AM, Khalek N, Peranteau WH, Howell LJ, Adzick NS, Coleman BG. Two's Company: Multiple Thoracic Lesions on Prenatal US and MRI. Fetal Diagn Ther. 2020 Jan; 47(8): 642-652. PubMed PMID: 32599594
Alapati D, Zacharias WJ, Hartman HA, Rossidis AC, Stratigis JD, Ahn NJ, Coons B, Zhou S, Li H, Singh K, Katzen J, Tomer Y, Chadwick AC, Musunuru K, Beers MF, Morrisey EE, Peranteau WH. In utero gene editing for monogenic lung disease. Sci Transl Med. 2019 Apr; 11(488): eaav8375. PubMed PMID: 30996081
Almeida-Porada G, Waddington SN, Chan JKY, Peranteau WH, MacKenzie T, Porada CD. In Utero Gene Therapy Consensus Statement from the IFeTIS. Mol Ther. 2019 Apr; 27(4): 705-707. PubMed PMID: 30837116
Rossidis AC, Angelin A, Lawrence KM, Baumgarten HD, Kim AG, Mejaddam AY, Coons BE, Hartman HA, Hwang G, Monos S, Peranteau WH, Davey MG, Murdock D, Wallace DC, Flake AW. Premature Lambs Exhibit Normal Mitochondrial Respiration after Long-Term Extrauterine Support. Fetal Diagn Ther. 2019 Jan; 46(5): 306-312. PubMed PMID: 30861524